C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: PH domain and leucine rich repeat protein phosphatase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000040199 PHLPP2 9606 - 16:71637835-71724701 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000393524 PHLPP2-004 71644928-71715529 protein_coding
  ENST00000538126 PHLPP2-002 71676588-71723812 retained_intron
  ENST00000564884 PHLPP2-006 71637836-71663971 nonsense_mediated_decay
  ENST00000567016 PHLPP2-003 71648170-71723882 protein_coding
  ENST00000568004 PHLPP2-005 71637835-71681854 nonsense_mediated_decay
  ENST00000568954 PHLPP2-001 71644924-71724701 protein_coding
  ENST00000574977 PHLPP2-009 71678923-71684657 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastHeartKidneyLiverLungMuscleOvaryPlacentaENST00000393524ENST00000538126ENST00000564884ENST00000567016ENST00000568004ENST00000568954
Transcript ID Adipose Adrenal Bladder Brain Breast Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000393524 0.337±0.00 0.880±0.00 N/A 0.701±0.00 0.342±0.00 0.090±0.03 0.668±0.22 0.351±0.21 0.369±0.02 0.321±0.00 0.334±0.01 N/A
ENST00000538126 N/A N/A 0.614±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000564884 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.461±0.00 N/A 0.553±0.00
ENST00000567016 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.168±0.00 N/A N/A
ENST00000568004 N/A N/A 0.791±0.00 N/A N/A N/A 0.381±0.00 N/A N/A N/A N/A N/A
ENST00000568954 N/A 0.405±0.00 N/A N/A 0.416±0.00 N/A 0.424±0.00 N/A 0.356±0.00 0.042±0.00 N/A 0.277±0.11

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001917 IEA photoreceptor inner segment
GO:0003824 IEA catalytic activity
GO:0004722 IEA protein serine/threonine phosphatase activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006470 IEA protein dephosphorylation
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0008152 IEA metabolic process
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0042622 IEA photoreceptor outer segment membrane
GO:0045087 TAS innate immune response
GO:0046872 IEA metal ion binding
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000090255 phlpp2 PH domain and leucine rich repeat protein phosphatase 2 protein_coding Danio_rerio
ENSMUSG00000031732 Phlpp2 PH domain and leucine rich repeat protein phosphatase 2 protein_coding Mus_musculus

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