C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: reticulon 4 receptor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000040608 RTN4R 9606 - 22:20241415-20283246 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000043402 RTN4R-001 20241415-20268531 protein_coding
  ENST00000416372 RTN4R-002 20241415-20267689 protein_coding
  ENST00000425986 RTN4R-003 20241417-20243684 protein_coding
  ENST00000463936 RTN4R-005 20243020-20269365 processed_transcript
  ENST00000469601 RTN4R-006 20242597-20271747 processed_transcript
  ENST00000474642 RTN4R-007 20242849-20283246 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000043402ENST00000416372ENST00000425986ENST00000469601
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000043402 N/A 0.543±0.00 N/A 4.384±0.00 0.891±0.00 N/A N/A N/A N/A 1.680±0.00 N/A 8.454±0.00 0.700±0.00 N/A
ENST00000416372 0.380±0.00 0.329±0.00 0.200±0.00 5.681±1.06 0.821±0.00 0.399±0.00 0.234±0.11 1.155±0.31 0.648±0.00 N/A 0.056±0.00 3.047±1.46 2.540±0.72 0.934±0.40
ENST00000425986 N/A 0.403±0.00 N/A N/A N/A N/A N/A 0.399±0.00 N/A N/A N/A N/A N/A 0.264±0.00
ENST00000469601 N/A N/A 0.413±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00086B CIL_00086B_0001 VISTA 22:20120771-20724717

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004872 NAS receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005783 IDA endoplasmic reticulum
GO:0005886 TAS plasma membrane
GO:0007409 NAS axonogenesis
GO:0009986 IDA cell surface
GO:0030426 IEA growth cone
GO:0031225 IEA anchored component of membrane
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0050770 TAS regulation of axonogenesis
GO:0050771 TAS negative regulation of axonogenesis
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000089918 rtn4r reticulon 4 receptor protein_coding Danio_rerio
ENSDARG00000090035 rtn4r reticulon 4 receptor protein_coding Danio_rerio
ENSMUSG00000043811 Rtn4r reticulon 4 receptor protein_coding Mus_musculus

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