C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000047249 ATP6V1H 9606 - 8:53715557-53843558 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000355221 ATP6V1H-001 53715557-53843558 protein_coding
  ENST00000359530 ATP6V1H-002 53715673-53843262 protein_coding
  ENST00000396774 ATP6V1H-005 53715731-53843042 protein_coding
  ENST00000518072 ATP6V1H-019 53715670-53743715 retained_intron
  ENST00000519588 ATP6V1H-013 53814732-53843245 nonsense_mediated_decay
  ENST00000519922 ATP6V1H-012 53832865-53839838 retained_intron
  ENST00000520188 ATP6V1H-004 53715673-53839961 protein_coding
  ENST00000521275 ATP6V1H-010 53829444-53843017 protein_coding
  ENST00000521335 ATP6V1H-003 53831789-53843259 retained_intron
  ENST00000521377 ATP6V1H-008 53814675-53833189 retained_intron
  ENST00000521707 ATP6V1H-011 53756262-53772065 retained_intron
  ENST00000521900 ATP6V1H-015 53769654-53817465 processed_transcript
  ENST00000522159 ATP6V1H-018 53715673-53739623 processed_transcript
  ENST00000522849 ATP6V1H-014 53795750-53817503 nonsense_mediated_decay
  ENST00000523343 ATP6V1H-020 53715673-53795761 processed_transcript
  ENST00000523426 ATP6V1H-017 53743587-53801868 processed_transcript
  ENST00000523899 ATP6V1H-021 53715683-53769688 processed_transcript
  ENST00000524164 ATP6V1H-009 53715900-53843293 nonsense_mediated_decay
  ENST00000524234 ATP6V1H-006 53829446-53842899 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000355221ENST00000359530ENST00000396774ENST00000518072ENST00000519588ENST00000521335ENST00000521377ENST00000523426ENST00000523899ENST00000524164
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000355221 N/A N/A N/A 21.633±3.20 N/A 2.008±0.00 N/A 0.518±0.00 N/A N/A 0.847±0.00 N/A N/A N/A
ENST00000359530 5.535±0.00 4.564±0.00 2.126±0.00 N/A 4.984±3.06 4.283±0.00 5.314±3.62 23.701±0.00 3.116±0.38 4.774±0.00 2.839±1.67 7.334±4.57 14.499±1.61 7.506±0.00
ENST00000396774 N/A 2.904±0.00 N/A 11.965±0.00 N/A N/A N/A N/A N/A N/A N/A 1.507±0.75 N/A N/A
ENST00000518072 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.977±0.00 N/A N/A N/A
ENST00000519588 N/A N/A N/A N/A N/A N/A N/A 3.014±0.00 N/A N/A N/A N/A N/A N/A
ENST00000521335 N/A N/A N/A N/A N/A N/A N/A 0.868±0.00 N/A 2.392±0.00 N/A N/A N/A N/A
ENST00000521377 N/A N/A N/A N/A N/A 5.839±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000523426 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.864±0.00 N/A N/A N/A
ENST00000523899 N/A N/A N/A N/A N/A N/A N/A N/A 4.866±0.00 N/A N/A N/A N/A N/A
ENST00000524164 6.896±0.00 7.155±0.00 1.863±0.00 18.670±3.23 4.861±2.79 6.953±3.83 2.183±1.29 11.096±9.53 1.699±0.32 6.391±2.89 2.462±0.57 9.604±9.40 40.604±0.00 19.501±8.99

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008TN CIL_0008TN_0001 VISTA 8:53576629-54178623

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000221 IEA:NAS vacuolar proton-transporting V-type ATPase, V1 domain
GO:0005488 IEA binding
GO:0005515 IPI protein binding
GO:0005765 IDA lysosomal membrane
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0006200 NAS ATP catabolic process
GO:0006879 TAS cellular iron ion homeostasis
GO:0006897 IDA endocytosis
GO:0007035 NAS vacuolar acidification
GO:0008286 TAS insulin receptor signaling pathway
GO:0015991 IEA:NAS ATP hydrolysis coupled proton transport
GO:0016032 TAS viral process
GO:0016820 IEA hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
GO:0016887 NAS ATPase activity
GO:0030234 NAS enzyme regulator activity
GO:0033572 TAS transferrin transport
GO:0046961 IEA proton-transporting ATPase activity, rotational mechanism
GO:0050690 TAS regulation of defense response to virus by virus
GO:0050790 NAS regulation of catalytic activity
GO:0051701 TAS interaction with host
GO:0055085 TAS transmembrane transport
GO:0070062 IDA extracellular vesicular exosome
GO:0090382 TAS phagosome maturation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006370 atp6v1h ATPase, H+ transporting, lysosomal, V1 subunit H protein_coding Danio_rerio
ENSMUSG00000033793 Atp6v1h ATPase, H+ transporting, lysosomal V1 subunit H protein_coding Mus_musculus

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