C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hexosaminidase B (beta polypeptide)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000049860 HEXB 9606 + 5:74640023-74722647 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261416 HEXB-001 74685144-74721288 protein_coding
  ENST00000503312 HEXB-013 74716629-74722616 nonsense_mediated_decay
  ENST00000504459 HEXB-008 74713538-74720836 retained_intron
  ENST00000505859 HEXB-011 74720488-74722647 nonsense_mediated_decay
  ENST00000509579 HEXB-009 74719989-74721288 protein_coding
  ENST00000510820 HEXB-006 74693475-74705257 retained_intron
  ENST00000511181 HEXB-002 74640023-74721288 protein_coding
  ENST00000511621 HEXB-010 74715646-74716829 retained_intron
  ENST00000513079 HEXB-003 74685196-74706168 retained_intron
  ENST00000513336 HEXB-007 74715586-74721288 protein_coding
  ENST00000513539 HEXB-004 74718291-74721287 processed_transcript
  ENST00000513867 HEXB-012 74721057-74722629 retained_intron
  ENST00000515528 HEXB-005 74685206-74689849 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000261416ENST00000504459ENST00000513336ENST00000513539
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000261416 37.780±0.00 40.708±0.00 10.468±0.00 21.218±0.00 30.021±13.51 26.857±18.68 38.013±0.00 39.636±17.46 35.658±15.58 19.316±0.00 39.584±0.61 275.165±142.96 36.567±0.00
ENST00000504459 N/A N/A N/A N/A N/A N/A 33.286±0.00 N/A 33.984±0.00 6.123±0.00 31.723±0.00 357.923±0.00 N/A
ENST00000513336 N/A N/A N/A 51.154±0.00 N/A N/A 46.138±0.00 N/A N/A N/A N/A N/A N/A
ENST00000513539 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 112.778±0.00 535.000±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001501 IEA skeletal system development
GO:0001669 IEA acrosomal vesicle
GO:0004553 IEA hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004563 IEA beta-N-acetylhexosaminidase activity
GO:0005764 IEA lysosome
GO:0005975 TAS:IEA carbohydrate metabolic process
GO:0006665 TAS sphingolipid metabolic process
GO:0006687 TAS glycosphingolipid metabolic process
GO:0006689 IEA ganglioside catabolic process
GO:0006874 IEA cellular calcium ion homeostasis
GO:0007040 IEA lysosome organization
GO:0007338 IEA single fertilization
GO:0007341 IEA penetration of zona pellucida
GO:0007605 IEA sensory perception of sound
GO:0007626 IEA locomotory behavior
GO:0008049 IEA male courtship behavior
GO:0008219 IEA cell death
GO:0008360 IEA regulation of cell shape
GO:0008654 IEA phospholipid biosynthetic process
GO:0009313 IEA oligosaccharide catabolic process
GO:0016020 IDA membrane
GO:0019915 IEA lipid storage
GO:0019953 IEA sexual reproduction
GO:0030203 TAS glycosaminoglycan metabolic process
GO:0030204 TAS chondroitin sulfate metabolic process
GO:0030207 TAS chondroitin sulfate catabolic process
GO:0030212 TAS hyaluronan metabolic process
GO:0030214 TAS hyaluronan catabolic process
GO:0031323 IEA regulation of cellular metabolic process
GO:0042339 TAS keratan sulfate metabolic process
GO:0042340 TAS keratan sulfate catabolic process
GO:0042552 IEA myelination
GO:0042803 IDA protein homodimerization activity
GO:0043202 TAS lysosomal lumen
GO:0043615 IEA astrocyte cell migration
GO:0044267 IEA cellular protein metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IDA protein heterodimerization activity
GO:0048477 IEA oogenesis
GO:0050885 IEA neuromuscular process controlling balance
GO:0050905 IEA neuromuscular process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000034368 hexb hexosaminidase B (beta polypeptide) protein_coding Danio_rerio
ENSMUSG00000021665 Hexb hexosaminidase B protein_coding Mus_musculus

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