C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mitogen-activated protein kinase 9
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000050748 MAPK9 9606 - 5:180233143-180292099 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000343111 MAPK9-002 180233594-180292099 protein_coding
  ENST00000347470 MAPK9-006 180236187-180292092 protein_coding
  ENST00000393360 MAPK9-003 180233594-180292056 protein_coding
  ENST00000393362 MAPK9-007 180242578-180292037 nonsense_mediated_decay
  ENST00000397072 MAPK9-201 180238309-180280581 protein_coding
  ENST00000425491 MAPK9-005 180246028-180291967 protein_coding
  ENST00000452135 MAPK9-001 180233143-180292099 protein_coding
  ENST00000455781 MAPK9-004 180233594-180292071 protein_coding
  ENST00000520212 MAPK9-010 180236526-180242900 retained_intron
  ENST00000523135 MAPK9-008 180253507-180264842 processed_transcript
  ENST00000523583 MAPK9-012 180264781-180292053 protein_coding
  ENST00000524170 MAPK9-011 180242728-180263089 processed_transcript
  ENST00000539014 MAPK9-202 180246545-180280581 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000347470ENST00000393360ENST00000397072ENST00000452135ENST00000455781ENST00000520212ENST00000524170
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000347470 4.676±0.00 4.389±0.00 N/A N/A 4.593±0.00 4.686±0.00 5.202±0.00 3.939±0.00 N/A 4.727±0.00 2.702±0.00 3.957±0.32 5.803±0.79 2.575±0.00
ENST00000393360 1.178±0.00 3.778±0.00 0.898±0.00 N/A 3.623±1.64 2.764±1.43 3.805±3.32 3.837±0.00 2.434±0.70 2.839±0.91 2.976±1.07 2.739±1.20 3.178±0.96 3.267±1.04
ENST00000397072 N/A N/A N/A N/A 2.048±0.00 N/A N/A 1.535±0.00 N/A N/A N/A 5.391±0.00 7.135±0.00 6.019±0.00
ENST00000452135 N/A N/A N/A N/A N/A 0.856±0.00 0.481±0.00 0.951±0.00 N/A N/A N/A 1.304±0.31 N/A N/A
ENST00000455781 N/A 1.992±0.00 N/A 7.606±3.03 1.024±0.24 1.373±0.00 N/A 0.727±0.25 N/A N/A 0.904±0.00 1.366±0.16 N/A 2.764±0.00
ENST00000520212 N/A N/A 0.590±0.00 N/A 2.117±0.00 1.039±0.00 N/A N/A N/A 1.790±0.00 N/A N/A N/A N/A
ENST00000524170 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.068±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000XG CIL_0000XG_0002 CGP 5:180233143-180353387

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000165 IEA MAPK cascade
GO:0001836 IEA release of cytochrome c from mitochondria
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002755 TAS MyD88-dependent toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0003824 IEA catalytic activity
GO:0004672 IEA protein kinase activity
GO:0004705 IDA JUN kinase activity
GO:0004707 IEA MAP kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005829 TAS cytosol
GO:0006468 IEA protein phosphorylation
GO:0006626 IEA protein targeting to mitochondrion
GO:0006919 IEA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006950 TAS response to stress
GO:0007254 IDA JNK cascade
GO:0007258 IEA JUN phosphorylation
GO:0007417 IEA central nervous system development
GO:0008134 IDA transcription factor binding
GO:0008656 IEA cysteine-type endopeptidase activator activity involved in apoptotic process
GO:0009103 IEA lipopolysaccharide biosynthetic process
GO:0009612 IEA response to mechanical stimulus
GO:0009636 IEA response to toxic substance
GO:0010033 IEA response to organic substance
GO:0010628 IMP positive regulation of gene expression
GO:0010744 IMP positive regulation of macrophage derived foam cell differentiation
GO:0010770 IEA positive regulation of cell morphogenesis involved in differentiation
GO:0014075 IEA response to amine
GO:0016020 IEA membrane
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0016773 IEA phosphotransferase activity, alcohol group as acceptor
GO:0031175 IEA neuron projection development
GO:0031394 IEA positive regulation of prostaglandin biosynthetic process
GO:0031396 IEA regulation of protein ubiquitination
GO:0031435 IEA mitogen-activated protein kinase kinase kinase binding
GO:0032308 IEA positive regulation of prostaglandin secretion
GO:0032722 IEA positive regulation of chemokine production
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034146 TAS toll-like receptor 5 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0034166 TAS toll-like receptor 10 signaling pathway
GO:0034644 IEA cellular response to UV
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0042493 IEA response to drug
GO:0043065 IEA positive regulation of apoptotic process
GO:0043280 IEA positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045087 TAS innate immune response
GO:0045429 IEA positive regulation of nitric oxide biosynthetic process
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0046328 IEA regulation of JNK cascade
GO:0046686 IEA response to cadmium ion
GO:0051090 TAS regulation of sequence-specific DNA binding transcription factor activity
GO:0051403 TAS stress-activated MAPK cascade
GO:0051770 IEA positive regulation of nitric-oxide synthase biosynthetic process
GO:0071222 IEA cellular response to lipopolysaccharide
GO:0071347 IEA cellular response to interleukin-1
GO:0071356 IEA cellular response to tumor necrosis factor
GO:0071363 IEA cellular response to growth factor stimulus
GO:2001235 IEA positive regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077364 mapk9 mitogen-activated protein kinase 9 protein_coding Danio_rerio
ENSMUSG00000020366 Mapk9 mitogen-activated protein kinase 9 protein_coding Mus_musculus

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