C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome b-245, alpha polypeptide
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000051523 CYBA 9606 - 16:88643283-88651152 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261623 CYBA-001 88643283-88651152 protein_coding
  ENST00000561972 CYBA-007 88647693-88651054 processed_transcript
  ENST00000562209 CYBA-010 88646141-88651031 retained_intron
  ENST00000563526 CYBA-004 88645965-88650988 retained_intron
  ENST00000565588 CYBA-008 88643514-88646825 protein_coding
  ENST00000566229 CYBA-011 88643540-88650314 protein_coding
  ENST00000566534 CYBA-009 88643514-88651035 retained_intron
  ENST00000567174 CYBA-005 88644742-88651041 protein_coding
  ENST00000568278 CYBA-006 88646132-88651015 protein_coding
  ENST00000569359 CYBA-003 88645087-88651030 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000261623ENST00000566229ENST00000566534ENST00000567174ENST00000569359
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000261623 251.985±0.00 757.541±0.00 3.029±0.00 25.109±19.44 127.691±107.56 89.171±63.64 23.508±17.39 90.545±85.02 28.474±19.25 191.995±164.48 8.717±1.31 70.021±66.07 137.284±88.91 45.763±45.44
ENST00000566229 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 46.176±0.00 41.744±22.02 0.432±0.00
ENST00000566534 N/A N/A 2.176±0.00 N/A 3.161±0.00 4.329±0.00 N/A N/A N/A N/A 1.129±0.00 3.481±0.00 N/A N/A
ENST00000567174 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.422±0.00 5.219±0.00 N/A 0.540±0.00
ENST00000569359 N/A N/A 0.748±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 5.640±0.00 N/A 0.507±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002SW CIL_0002SW_0001 CGP 16:88638591-88651152
CIL_00032Y CIL_00032Y_0001 CGP 16:88643283-88663161

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001938 IEA positive regulation of endothelial cell proliferation
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0003106 IEA negative regulation of glomerular filtration by angiotensin
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005768 IEA endosome
GO:0005794 IEA Golgi apparatus
GO:0006801 IMP superoxide metabolic process
GO:0006954 IMP inflammatory response
GO:0008217 IEA regulation of blood pressure
GO:0009055 IDA electron carrier activity
GO:0014895 ISS smooth muscle hypertrophy
GO:0016020 IDA membrane
GO:0016175 IMP superoxide-generating NADPH oxidase activity
GO:0016324 IEA apical plasma membrane
GO:0017004 IDA cytochrome complex assembly
GO:0017124 IPI SH3 domain binding
GO:0020037 IEA heme binding
GO:0030141 TAS secretory granule
GO:0030307 IEA positive regulation of cell growth
GO:0030425 IEA dendrite
GO:0030670 TAS phagocytic vesicle membrane
GO:0031667 IEA response to nutrient levels
GO:0042493 IEA response to drug
GO:0042554 IMP superoxide anion generation
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0043020 IMP NADPH oxidase complex
GO:0043025 IEA neuronal cell body
GO:0045087 IMP innate immune response
GO:0045730 IMP respiratory burst
GO:0046872 IEA metal ion binding
GO:0046982 IPI protein heterodimerization activity
GO:0050665 ISS hydrogen peroxide biosynthetic process
GO:0051279 IEA regulation of release of sequestered calcium ion into cytosol
GO:0051701 TAS interaction with host
GO:0055114 IMP oxidation-reduction process
GO:0070257 IEA positive regulation of mucus secretion
GO:0070555 IEA response to interleukin-1
GO:0071230 IEA cellular response to amino acid stimulus
GO:0071260 IEA cellular response to mechanical stimulus
GO:0071310 IEA cellular response to organic substance
GO:0071333 IEA cellular response to glucose stimulus
GO:0071356 IEA cellular response to tumor necrosis factor
GO:0071407 IEA cellular response to organic cyclic compound
GO:0071480 IEA cellular response to gamma radiation
GO:0072593 IEA reactive oxygen species metabolic process
GO:0090382 TAS phagosome maturation
GO:0097038 IEA perinuclear endoplasmic reticulum

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018283 cyba cytochrome b-245, alpha polypeptide protein_coding Danio_rerio
ENSMUSG00000006519 Cyba cytochrome b-245, alpha polypeptide protein_coding Mus_musculus

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