C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protease, serine, 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000052344 PRSS8 9606 - 16:31131433-31135762 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000317508 PRSS8-001 31131433-31135762 protein_coding
  ENST00000564025 PRSS8-006 31133200-31135727 retained_intron
  ENST00000567531 PRSS8-005 31132439-31135640 protein_coding
  ENST00000567797 PRSS8-004 31132879-31135727 protein_coding
  ENST00000567833 PRSS8-002 31134042-31135703 retained_intron
  ENST00000568261 PRSS8-003 31131894-31135727 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000317508ENST00000564025ENST00000567531ENST00000567797ENST00000567833ENST00000568261
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000317508 0.059±0.00 0.043±0.00 1.595±0.00 N/A 6.377±0.95 4.428±0.26 N/A 46.449±0.00 2.422±2.11 57.506±0.00 N/A 15.907±18.88 129.703±69.76 2.715±2.63
ENST00000564025 N/A N/A N/A N/A N/A N/A 0.217±0.00 N/A N/A N/A 0.215±0.00 N/A N/A N/A
ENST00000567531 N/A N/A 3.026±0.00 0.180±0.01 N/A N/A 0.019±0.00 N/A N/A 1.280±0.00 N/A 23.823±0.00 N/A 0.066±0.00
ENST00000567797 0.161±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000567833 0.085±0.00 0.317±0.00 N/A 0.102±0.00 N/A N/A 0.013±0.00 N/A N/A N/A N/A 0.884±0.00 N/A 0.044±0.00
ENST00000568261 0.173±0.00 N/A N/A 0.138±0.00 N/A N/A 0.058±0.00 N/A 1.323±0.00 N/A N/A 20.938±0.00 N/A 2.003±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00035R CIL_00035R_0001 CGP 16:31115754-31135762
CIL_00035U CIL_00035U_0001 CGP 16:31131433-31150094

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004252 IEA serine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005615 IDA extracellular space
GO:0005886 IDA plasma membrane
GO:0006508 IEA proteolysis
GO:0008236 TAS serine-type peptidase activity
GO:0010765 IEA positive regulation of sodium ion transport
GO:0016021 IEA integral component of membrane
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000030800 Prss8 protease, serine 8 (prostasin) protein_coding Mus_musculus

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