C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serpin peptidase inhibitor, clade B (ovalbumin), member 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000057149 SERPINB3 9606 - 18:63637719-63661963 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000283752 SERPINB3-001 63655197-63661963 protein_coding
  ENST00000332821 SERPINB3-002 63655198-63661884 protein_coding
  ENST00000356424 SERPINB3-201 63637719-63661216 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; ColonKidneyLungOvaryTestisENST00000283752ENST00000332821ENST00000356424
Transcript ID Colon Kidney Lung Ovary Testis
ENST00000283752 0.019±0.00 N/A 3.645±0.01 5.793±3.52 0.369±0.00
ENST00000332821 N/A N/A N/A N/A 0.727±0.00
ENST00000356424 N/A 0.030±0.00 6.479±3.78 3.719±1.71 0.437±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000160 CIL_000160_0009 CGP 18:63586989-63644298
CIL_000160 CIL_000160_000B CGP 18:63637259-63661963
CIL_000160 CIL_000160_0004 CGP 18:63637719-63726432

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001618 IDA virus receptor activity
GO:0004867 IBA serine-type endopeptidase inhibitor activity
GO:0005576 IBA extracellular region
GO:0005615 IEA extracellular space
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0009615 IDA response to virus
GO:0010466 IDA negative regulation of peptidase activity
GO:0010951 IBA negative regulation of endopeptidase activity
GO:0030162 IBA regulation of proteolysis
GO:0031982 IDA vesicle
GO:0043086 IDA negative regulation of catalytic activity
GO:0045861 IDA negative regulation of proteolysis
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014556 serpinb1l3 serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 3 protein_coding Danio_rerio
ENSDARG00000057263 zgc:173729 zgc:173729 protein_coding Danio_rerio
ENSDARG00000091801 si:ch73-303g23.4 si:ch73-303g23.4 protein_coding Danio_rerio
ENSDARG00000095830 serpinb1l1 serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 1 protein_coding Danio_rerio
ENSDARG00000096888 serpinb1l4 serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 4 protein_coding Danio_rerio
ENSMUSG00000044594 Serpinb3a serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A protein_coding Mus_musculus
ENSMUSG00000058017 Serpinb3d serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3D protein_coding Mus_musculus
ENSMUSG00000073601 Serpinb3c serine (or cysteine) peptidase inhibitor, clade B, member 3C protein_coding Mus_musculus
ENSMUSG00000073602 Serpinb3b serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3B protein_coding Mus_musculus

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