C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: polymerase (RNA) III (DNA directed) polypeptide E (80kD)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000058600 POLR3E 9606 + 16:22297375-22335103 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000299853 POLR3E-001 22297409-22335103 protein_coding
  ENST00000359210 POLR3E-004 22297433-22334025 protein_coding
  ENST00000418581 POLR3E-003 22297427-22334061 protein_coding
  ENST00000561494 POLR3E-011 22297434-22309463 nonsense_mediated_decay
  ENST00000563024 POLR3E-009 22297434-22313660 protein_coding
  ENST00000563282 POLR3E-017 22328319-22333696 retained_intron
  ENST00000563766 POLR3E-006 22302470-22310321 retained_intron
  ENST00000564061 POLR3E-005 22297455-22329091 retained_intron
  ENST00000564209 POLR3E-002 22297411-22333935 protein_coding
  ENST00000564256 POLR3E-014 22302974-22309945 processed_transcript
  ENST00000564750 POLR3E-007 22302954-22333935 nonsense_mediated_decay
  ENST00000564883 POLR3E-013 22297430-22309476 protein_coding
  ENST00000565117 POLR3E-008 22331435-22334441 retained_intron
  ENST00000565358 POLR3E-012 22297420-22313654 protein_coding
  ENST00000565551 POLR3E-016 22308962-22318845 nonsense_mediated_decay
  ENST00000567022 POLR3E-010 22302806-22308481 retained_intron
  ENST00000569757 POLR3E-015 22314914-22322872 protein_coding
  ENST00000569787 POLR3E-018 22316981-22325359 retained_intron
  ENST00000615879 POLR3E-201 22297375-22335101 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000299853ENST00000359210ENST00000418581ENST00000563282ENST00000564061ENST00000564209ENST00000564750ENST00000565117ENST00000565551ENST00000615879
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000299853 N/A N/A N/A 1.559±0.00 N/A N/A N/A 0.661±0.00 N/A 0.577±0.00 N/A 2.569±0.00 1.395±0.00 N/A
ENST00000359210 N/A N/A N/A N/A N/A N/A N/A 0.844±0.00 1.134±0.07 0.717±0.00 N/A 4.891±0.00 3.235±0.00 N/A
ENST00000418581 7.303±0.00 3.747±0.00 N/A 1.260±0.00 4.047±0.00 2.351±0.00 2.326±0.00 N/A 1.747±0.81 N/A 13.761±0.00 4.898±3.46 5.470±2.15 6.709±0.18
ENST00000563282 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 8.046±0.00 10.822±0.00 17.187±0.00
ENST00000564061 N/A 2.350±0.00 N/A N/A N/A 0.862±0.00 N/A N/A N/A 0.792±0.00 1.165±0.00 1.376±0.29 N/A 1.871±0.00
ENST00000564209 4.814±0.00 4.212±0.00 1.344±0.00 1.275±0.00 3.052±1.97 N/A 1.938±0.00 N/A N/A 3.626±0.00 3.269±0.00 1.558±0.00 2.746±0.00 4.923±0.00
ENST00000564750 N/A N/A 0.470±0.00 2.472±1.51 3.394±2.08 4.873±2.08 5.676±0.00 4.934±0.00 2.722±0.00 6.305±0.00 9.429±4.54 2.701±0.32 3.490±0.00 3.388±0.00
ENST00000565117 N/A 2.559±0.00 1.219±0.00 1.717±0.14 2.064±0.00 1.439±0.00 0.882±0.00 1.956±0.00 1.356±0.69 1.801±0.00 N/A 2.341±0.45 N/A 2.823±1.32
ENST00000565551 N/A N/A N/A N/A N/A N/A N/A 1.844±0.00 N/A N/A N/A N/A N/A N/A
ENST00000615879 N/A N/A N/A N/A N/A 1.070±0.00 N/A 1.576±0.00 0.745±0.00 N/A N/A N/A N/A 1.234±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005T8 CIL_0005T8_0001 CGP 16:22206282-22335103
CIL_0006GX CIL_0006GX_0001 CGP 16:22297375-22437165

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001056 IBA RNA polymerase III activity
GO:0003899 IEA DNA-directed RNA polymerase activity
GO:0005634 IEA:IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005666 IBA DNA-directed RNA polymerase III complex
GO:0005813 IDA centrosome
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006383 TAS transcription from RNA polymerase III promoter
GO:0006385 TAS transcription elongation from RNA polymerase III promoter
GO:0006386 TAS termination of RNA polymerase III transcription
GO:0010467 TAS gene expression
GO:0032481 TAS positive regulation of type I interferon production
GO:0045087 TAS innate immune response
GO:0051607 IEA defense response to virus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037358 polr3e polymerase (RNA) III (DNA directed) polypeptide E protein_coding Danio_rerio
ENSMUSG00000030880 Polr3e polymerase (RNA) III (DNA directed) polypeptide E protein_coding Mus_musculus

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