C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: calponin 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000064666 CNN2 9606 + 19:1026581-1039068 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263097 CNN2-001 1026581-1039068 protein_coding
  ENST00000348419 CNN2-003 1026610-1039068 protein_coding
  ENST00000562015 CNN2-007 1026586-1032695 protein_coding
  ENST00000562075 CNN2-006 1026691-1036677 protein_coding
  ENST00000562958 CNN2-005 1026629-1039068 protein_coding
  ENST00000564572 CNN2-011 1036799-1039064 retained_intron
  ENST00000565096 CNN2-004 1026618-1039068 protein_coding
  ENST00000566695 CNN2-008 1030943-1037733 protein_coding
  ENST00000568865 CNN2-009 1031137-1038309 protein_coding
  ENST00000569352 CNN2-013 1026629-1037632 nonsense_mediated_decay
  ENST00000606983 CNN2-014 1026662-1036472 protein_coding
  ENST00000607102 CNN2-010 1026691-1036688 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000263097ENST00000348419ENST00000562958ENST00000565096ENST00000566695ENST00000568865
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000263097 24.677±0.00 16.439±0.00 N/A 4.992±0.00 23.945±20.48 1.258±0.00 8.183±5.50 9.970±9.14 9.411±0.00 82.052±78.24 5.780±0.00 73.516±48.78 19.272±7.00 4.222±0.28
ENST00000348419 N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.490±0.00 N/A 32.748±0.00 N/A N/A
ENST00000562958 N/A N/A N/A N/A N/A 2.970±0.00 N/A N/A 3.012±0.00 N/A N/A N/A N/A N/A
ENST00000565096 N/A N/A N/A 0.565±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000566695 N/A N/A N/A N/A N/A 17.819±0.00 N/A N/A N/A N/A N/A 37.374±0.00 29.674±0.00 7.123±4.40
ENST00000568865 N/A N/A 32.851±0.00 2.622±0.00 10.358±0.00 6.379±0.00 3.464±1.02 4.497±0.00 13.614±0.00 21.551±0.00 1.112±0.00 24.135±0.00 N/A 1.305±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008XG CIL_0008XG_0001 VISTA 19:477571-1083531
CIL_0000I1 CIL_0000I1_0001 CGP 19:1009648-1039068
CIL_0000I2 CIL_0000I2_0001 CGP 19:1026581-1065572

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001725 IDA stress fiber
GO:0003779 IEA actin binding
GO:0005515 IEA protein binding
GO:0005516 IEA calmodulin binding
GO:0005856 TAS cytoskeleton
GO:0005911 TAS cell-cell junction
GO:0005925 IDA focal adhesion
GO:0007010 TAS cytoskeleton organization
GO:0010628 IEA positive regulation of gene expression
GO:0016020 IDA membrane
GO:0030097 IEA hemopoiesis
GO:0030336 IEA negative regulation of cell migration
GO:0031032 IEA actomyosin structure organization
GO:0032970 IDA regulation of actin filament-based process
GO:0042060 IEA wound healing
GO:0042127 IEA regulation of cell proliferation
GO:0050765 IEA negative regulation of phagocytosis
GO:0070062 IDA extracellular vesicular exosome
GO:0071260 IDA cellular response to mechanical stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035858 cnn2 calponin 2 protein_coding Danio_rerio
ENSMUSG00000004665 Cnn2 calponin 2 protein_coding Mus_musculus

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