C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: calcitonin receptor-like
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000064989 CALCRL 9606 - 2:187343129-187448460 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000392370 CALCRL-001 187343129-187448460 protein_coding
  ENST00000409998 CALCRL-002 187343129-187448460 protein_coding
  ENST00000410068 CALCRL-004 187345927-187448252 protein_coding
  ENST00000410102 CALCRL-005 187383244-187448252 protein_coding
  ENST00000447403 CALCRL-006 187380739-187448252 protein_coding
  ENST00000461244 CALCRL-007 187387666-187448252 processed_transcript
  ENST00000474212 CALCRL-008 187387338-187448252 processed_transcript
  ENST00000479784 CALCRL-003 187428337-187448146 processed_transcript
  ENST00000485973 CALCRL-009 187387399-187448253 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000392370ENST00000409998ENST00000410068
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000392370 2.834±0.00 2.540±0.00 N/A N/A 0.934±0.00 1.140±0.00 1.252±0.00 N/A 1.217±0.00 12.726±0.00 N/A 0.887±0.38 0.833±0.00 1.115±0.00
ENST00000409998 6.887±0.00 3.606±0.00 0.504±0.00 0.779±0.06 2.050±0.00 1.046±0.64 2.133±1.62 1.799±0.81 0.644±0.09 20.582±6.60 N/A 1.318±0.82 0.592±0.15 0.751±0.00
ENST00000410068 N/A N/A 2.321±0.00 0.757±0.00 3.146±0.00 3.439±0.00 2.421±0.54 1.808±0.00 3.871±0.00 27.676±0.00 0.664±0.30 4.378±0.00 0.621±0.14 0.731±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00042L CIL_00042L_0002 CGP 2:187343129-187565760

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IDA angiogenesis
GO:0001605 IDA adrenomedullin receptor activity
GO:0001635 IEA calcitonin gene-related peptide receptor activity
GO:0004888 IEA transmembrane signaling receptor activity
GO:0004930 TAS:IEA G-protein coupled receptor activity
GO:0004948 IEA calcitonin receptor activity
GO:0005515 IPI protein binding
GO:0005764 IDA lysosome
GO:0005768 IDA endosome
GO:0005783 IDA endoplasmic reticulum
GO:0005886 IDA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006171 IDA cAMP biosynthetic process
GO:0006816 IDA calcium ion transport
GO:0006937 IEA regulation of muscle contraction
GO:0007166 IEA cell surface receptor signaling pathway
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007187 TAS G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007189 IEA adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007507 IEA heart development
GO:0008284 IEA positive regulation of cell proliferation
GO:0008565 IDA protein transporter activity
GO:0015031 IDA protein transport
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030819 IDA positive regulation of cAMP biosynthetic process
GO:0031623 IDA receptor internalization
GO:0048661 IEA positive regulation of smooth muscle cell proliferation
GO:0050728 IEA negative regulation of inflammatory response
GO:0071329 IDA cellular response to sucrose stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011473 calcrla calcitonin receptor-like a protein_coding Danio_rerio
ENSDARG00000011571 calcrlb calcitonin receptor-like b protein_coding Danio_rerio
ENSMUSG00000059588 Calcrl calcitonin receptor-like protein_coding Mus_musculus

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