C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: importin 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000065150 IPO5 9606 + 13:97953658-98024297 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261574 IPO5-001 97953675-98024297 protein_coding
  ENST00000357602 IPO5-002 97960249-98022489 protein_coding
  ENST00000403772 IPO5-003 97976703-97990502 protein_coding
  ENST00000421861 IPO5-020 97960218-97985515 protein_coding
  ENST00000460070 IPO5-008 97953658-97985622 protein_coding
  ENST00000463157 IPO5-015 97953683-97985459 protein_coding
  ENST00000468620 IPO5-028 98018586-98019941 retained_intron
  ENST00000469360 IPO5-004 97976963-98022028 protein_coding
  ENST00000470493 IPO5-025 97993150-98000922 retained_intron
  ENST00000471898 IPO5-017 97953683-97985472 protein_coding
  ENST00000473582 IPO5-023 97979870-97990210 protein_coding
  ENST00000475420 IPO5-021 97975631-97990170 protein_coding
  ENST00000479736 IPO5-026 98002476-98006325 retained_intron
  ENST00000480611 IPO5-012 97953926-97985547 protein_coding
  ENST00000480641 IPO5-022 97976465-97989109 protein_coding
  ENST00000481455 IPO5-014 97953675-97985554 protein_coding
  ENST00000481689 IPO5-011 97953714-97985491 protein_coding
  ENST00000482642 IPO5-007 97953658-97969905 retained_intron
  ENST00000485433 IPO5-010 97953959-97982584 protein_coding
  ENST00000489058 IPO5-009 97953694-97976792 protein_coding
  ENST00000490369 IPO5-018 97953683-97982569 nonsense_mediated_decay
  ENST00000490680 IPO5-006 97976632-98021882 protein_coding
  ENST00000491555 IPO5-005 98001646-98022503 retained_intron
  ENST00000493122 IPO5-029 98019579-98021411 retained_intron
  ENST00000493281 IPO5-016 97953683-97982550 protein_coding
  ENST00000493492 IPO5-027 98003009-98007587 processed_transcript
  ENST00000496368 IPO5-019 97960192-97985489 protein_coding
  ENST00000497270 IPO5-024 97976675-97989099 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000261574ENST00000357602ENST00000469360ENST00000473582ENST00000490680ENST00000491555
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000261574 N/A N/A N/A N/A 2.539±0.00 2.837±0.00 1.280±0.00 1.664±0.00 5.794±0.00 1.923±0.00 3.182±0.00 10.549±4.65 N/A 19.111±6.34
ENST00000357602 6.032±0.00 6.547±0.00 N/A N/A 7.198±0.00 5.753±0.00 9.968±0.00 7.545±0.00 N/A 11.025±0.00 19.736±0.00 13.894±5.64 5.327±0.25 19.233±0.00
ENST00000469360 10.787±0.00 N/A 4.235±0.00 10.774±1.68 10.863±2.47 9.719±2.62 3.398±0.00 7.837±2.86 14.536±0.00 9.035±0.00 11.152±1.71 22.798±8.84 9.142±6.20 104.709±76.39
ENST00000473582 N/A N/A N/A N/A N/A N/A N/A 19.326±0.00 N/A N/A N/A N/A N/A N/A
ENST00000490680 9.616±0.00 N/A N/A N/A N/A N/A 7.065±0.00 N/A N/A N/A 11.299±0.00 N/A N/A 33.412±0.00
ENST00000491555 N/A 8.192±0.00 1.273±0.00 5.140±0.00 2.438±0.00 N/A N/A N/A 4.153±0.00 3.268±0.00 N/A 19.510±12.32 13.723±0.00 41.206±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000O3 CIL_0000O3_0001 CGP 13:97434222-98024297
CIL_0004FZ CIL_0004FZ_0002 CGP 13:97953658-98455176

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005095 TAS GTPase inhibitor activity
GO:0005488 IEA binding
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA:ISS nucleus
GO:0005643 TAS nuclear pore
GO:0005737 IDA:ISS cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0006607 ISS NLS-bearing protein import into nucleus
GO:0006610 IDA ribosomal protein import into nucleus
GO:0006886 IEA intracellular protein transport
GO:0008536 IEA Ran GTPase binding
GO:0008565 ISS protein transporter activity
GO:0016020 IDA membrane
GO:0016032 IEA viral process
GO:0031965 IDA nuclear membrane
GO:0042307 ISS positive regulation of protein import into nucleus
GO:0043086 TAS negative regulation of catalytic activity
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0044822 IDA poly(A) RNA binding
GO:0071230 ISS cellular response to amino acid stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040245 kpnb3 karyopherin (importin) beta 3 protein_coding Danio_rerio
ENSMUSG00000030662 Ipo5 importin 5 protein_coding Mus_musculus

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