C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein disulfide isomerase family A, member 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000065485 PDIA5 9606 + 3:123067062-123225227 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000316218 PDIA5-001 123067070-123162104 protein_coding
  ENST00000467157 PDIA5-003 123144507-123162103 processed_transcript
  ENST00000469649 PDIA5-008 123150339-123225227 nonsense_mediated_decay
  ENST00000472319 PDIA5-006 123124066-123146258 processed_transcript
  ENST00000484644 PDIA5-004 123067348-123106842 protein_coding
  ENST00000485208 PDIA5-007 123144676-123150365 processed_transcript
  ENST00000489923 PDIA5-002 123067062-123162104 nonsense_mediated_decay
  ENST00000495004 PDIA5-005 123089107-123111007 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000316218ENST00000484644ENST00000489923ENST00000495004
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000316218 7.818±0.00 12.484±0.00 0.605±0.00 N/A 4.156±0.93 6.128±0.00 1.557±1.03 13.225±2.84 18.653±17.55 8.539±6.75 1.015±0.00 9.940±5.03 62.888±7.35 12.904±2.24
ENST00000484644 N/A N/A N/A N/A 8.610±0.00 N/A N/A N/A N/A N/A N/A 14.440±0.00 81.338±0.00 19.140±0.00
ENST00000489923 N/A N/A N/A 0.661±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000495004 N/A N/A 3.523±0.00 N/A N/A N/A N/A 16.557±0.00 N/A 5.517±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008J4 CIL_0008J4_0001 VISTA 3:122671455-123276444
CIL_000074 CIL_000074_0002 CGP 3:122909193-123225227
CIL_000073 CIL_000073_0002 CGP 3:123067062-123274130

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003756 IBA protein disulfide isomerase activity
GO:0005783 IBA endoplasmic reticulum
GO:0005788 TAS endoplasmic reticulum lumen
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006457 IBA protein folding
GO:0006987 TAS activation of signaling protein activity involved in unfolded protein response
GO:0016209 IEA antioxidant activity
GO:0016491 TAS:IEA oxidoreductase activity
GO:0030968 TAS endoplasmic reticulum unfolded protein response
GO:0034976 IBA response to endoplasmic reticulum stress
GO:0044267 TAS cellular protein metabolic process
GO:0045454 IEA cell redox homeostasis
GO:0055114 TAS:IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069242 pdia5 protein disulfide isomerase family A, member 5 protein_coding Danio_rerio
ENSMUSG00000022844 Pdia5 protein disulfide isomerase associated 5 protein_coding Mus_musculus

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