C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transducin-like enhancer of split 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000065717 TLE2 9606 - 19:2997638-3047635 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262953 TLE2-004 2997638-3029167 protein_coding
  ENST00000426948 TLE2-201 2997639-3045788 protein_coding
  ENST00000443826 TLE2-002 2997682-3029614 protein_coding
  ENST00000455444 TLE2-202 2997639-3029131 protein_coding
  ENST00000586422 TLE2-021 2997647-3028356 protein_coding
  ENST00000586492 TLE2-020 3005839-3008876 processed_transcript
  ENST00000587137 TLE2-015 3014597-3029043 protein_coding
  ENST00000587217 TLE2-013 3013747-3020589 processed_transcript
  ENST00000587672 TLE2-018 3009572-3019480 retained_intron
  ENST00000587770 TLE2-009 3019431-3025616 retained_intron
  ENST00000587893 TLE2-012 3019702-3025375 retained_intron
  ENST00000589205 TLE2-019 3009661-3019372 processed_transcript
  ENST00000589291 TLE2-014 3015715-3020227 processed_transcript
  ENST00000589364 TLE2-017 3005438-3025027 protein_coding
  ENST00000590101 TLE2-003 3014571-3028919 retained_intron
  ENST00000590183 TLE2-011 3014602-3025647 processed_transcript
  ENST00000590536 TLE2-006 2997848-3029013 protein_coding
  ENST00000591457 TLE2-016 3013791-3045730 protein_coding
  ENST00000591529 TLE2-001 2997646-3047635 protein_coding
  ENST00000591720 TLE2-007 3019553-3029622 retained_intron
  ENST00000592305 TLE2-010 3019500-3029034 retained_intron
  ENST00000592584 TLE2-008 3019301-3029613 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000262953ENST00000426948ENST00000443826ENST00000455444ENST00000586422ENST00000586492ENST00000587137ENST00000587672ENST00000589205ENST00000589364ENST00000590101ENST00000590183ENST00000590536ENST00000591457ENST00000592584
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000262953 13.193±0.00 8.718±0.00 N/A 1.181±1.04 19.608±0.00 14.711±0.00 8.486±0.00 3.634±0.00 3.136±0.00 12.753±0.00 12.353±0.00 12.900±10.07 3.219±0.99 7.289±0.00
ENST00000426948 N/A N/A N/A N/A N/A N/A N/A N/A 1.314±0.00 N/A 2.928±0.00 N/A 2.414±0.00 N/A
ENST00000443826 N/A 4.615±0.00 N/A N/A N/A 6.754±0.00 N/A N/A N/A N/A N/A 2.186±0.00 N/A N/A
ENST00000455444 6.115±0.00 5.111±0.00 N/A N/A N/A N/A N/A 7.975±0.00 N/A N/A N/A 1.960±0.00 2.442±0.00 N/A
ENST00000586422 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 29.458±0.00 25.938±0.00 18.460±0.00
ENST00000586492 N/A N/A N/A N/A N/A N/A N/A 2.328±0.00 N/A N/A N/A N/A N/A N/A
ENST00000587137 N/A N/A N/A 1.185±0.00 1.400±0.00 N/A N/A N/A 3.428±0.00 N/A 6.890±0.00 1.023±0.00 N/A N/A
ENST00000587672 N/A N/A 0.430±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000589205 43.221±0.00 24.556±0.00 N/A 9.336±0.00 51.171±0.00 N/A N/A N/A N/A N/A N/A 83.205±0.00 N/A 14.474±0.00
ENST00000589364 N/A N/A N/A N/A N/A N/A N/A 0.454±0.00 N/A 0.839±0.00 N/A 30.300±0.00 13.949±0.00 14.721±0.00
ENST00000590101 N/A N/A 0.542±0.00 N/A N/A 2.776±0.00 N/A N/A N/A N/A N/A 0.808±0.00 N/A N/A
ENST00000590183 N/A N/A N/A 1.190±0.00 N/A N/A N/A N/A N/A 0.919±0.00 4.434±0.00 N/A N/A N/A
ENST00000590536 N/A N/A 0.265±0.00 0.533±0.00 0.864±0.00 0.711±0.00 N/A 0.262±0.00 2.182±0.00 0.473±0.00 N/A 2.913±2.38 6.848±0.00 4.869±0.00
ENST00000591457 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.924±0.00 N/A 6.223±0.00
ENST00000592584 N/A N/A 2.742±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003714 IDA transcription corepressor activity
GO:0005515 IPI:IEA protein binding
GO:0005615 IDA extracellular space
GO:0005634 TAS nucleus
GO:0005654 TAS nucleoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007165 TAS signal transduction
GO:0007219 TAS Notch signaling pathway
GO:0009887 TAS organ morphogenesis
GO:0016055 IEA Wnt signaling pathway
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0090090 IDA negative regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000034771 Tle2 transducin-like enhancer of split 2, homolog of Drosophila E(spl) protein_coding Mus_musculus

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