C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: guanine nucleotide binding protein (G protein), beta 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000069966 GNB5 9606 - 15:52115105-52191369 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261837 GNB5-001 52115105-52191369 protein_coding
  ENST00000358784 GNB5-002 52122206-52180001 protein_coding
  ENST00000396335 GNB5-004 52120939-52179887 protein_coding
  ENST00000557936 GNB5-006 52121626-52128795 retained_intron
  ENST00000558122 GNB5-009 52141206-52144461 processed_transcript
  ENST00000558519 GNB5-010 52124473-52141211 nonsense_mediated_decay
  ENST00000559348 GNB5-005 52122209-52139955 processed_transcript
  ENST00000559541 GNB5-011 52124539-52135847 retained_intron
  ENST00000560075 GNB5-008 52147167-52191334 retained_intron
  ENST00000560085 GNB5-012 52123559-52128273 retained_intron
  ENST00000560116 GNB5-003 52149278-52179900 protein_coding
  ENST00000561313 GNB5-007 52135689-52179973 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000261837ENST00000358784ENST00000396335ENST00000557936ENST00000559348ENST00000561313
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000261837 N/A N/A N/A N/A N/A 0.388±0.00 N/A N/A 0.134±0.00 N/A N/A 0.760±0.71 N/A 0.791±0.22
ENST00000358784 3.117±0.00 5.060±0.00 1.642±0.00 8.828±3.01 1.926±0.18 2.626±1.53 0.896±0.68 8.293±0.00 2.357±0.11 0.968±0.40 0.303±0.14 8.330±6.75 2.544±0.56 8.204±3.59
ENST00000396335 1.667±0.00 2.499±0.00 N/A 1.420±0.00 0.747±0.35 3.070±0.00 0.855±0.00 6.313±0.00 2.312±0.00 1.525±0.00 0.556±0.00 3.869±2.05 1.541±0.17 4.704±2.74
ENST00000557936 N/A N/A N/A N/A N/A N/A N/A 0.632±0.00 0.886±0.00 N/A N/A 1.271±0.00 N/A N/A
ENST00000559348 N/A N/A 1.550±0.00 N/A N/A N/A 0.287±0.00 N/A N/A 0.986±0.00 N/A N/A N/A N/A
ENST00000561313 N/A N/A N/A N/A N/A N/A N/A N/A 3.125±0.00 N/A N/A 4.924±0.00 2.611±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003924 NAS GTPase activity
GO:0004871 NAS signal transducer activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IEA nucleus
GO:0005886 IEA plasma membrane
GO:0006184 NAS GTP catabolic process
GO:0007165 NAS signal transduction
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007603 TAS phototransduction, visible light
GO:0016056 TAS rhodopsin mediated signaling pathway
GO:0022400 TAS regulation of rhodopsin mediated signaling pathway
GO:0031682 IPI G-protein gamma-subunit binding
GO:0051087 IPI chaperone binding
GO:1901386 IDA negative regulation of voltage-gated calcium channel activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055377 gnb5b guanine nucleotide binding protein (G protein), beta 5b protein_coding Danio_rerio
ENSDARG00000092921 gnb5a guanine nucleotide binding protein (G protein), beta 5a protein_coding Danio_rerio
ENSMUSG00000032192 Gnb5 guanine nucleotide binding protein (G protein), beta 5 protein_coding Mus_musculus

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