C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: fibroblast growth factor 22
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000070388 FGF22 9606 + 19:639879-643703 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000215530 FGF22-001 639895-643703 protein_coding
  ENST00000586042 FGF22-002 639895-643703 protein_coding
  ENST00000591390 FGF22-003 639879-641590 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000215530ENST00000586042ENST00000591390
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000215530 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.239±0.00 N/A
ENST00000586042 0.480±0.00 N/A N/A 0.246±0.00 0.258±0.00 0.284±0.00 N/A N/A 0.111±0.00 0.503±0.00 0.294±0.00 0.632±0.00 0.225±0.00 0.593±0.00
ENST00000591390 0.185±0.00 0.402±0.00 0.037±0.00 0.494±0.00 0.210±0.00 0.311±0.00 0.070±0.00 0.414±0.00 0.093±0.00 0.229±0.00 0.041±0.00 0.247±0.15 0.088±0.03 0.348±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008XG CIL_0008XG_0001 VISTA 19:477571-1083531
CIL_0005ZL CIL_0005ZL_0002 CGP 19:617223-643703
CIL_00008H CIL_00008H_0001 CGP 19:639879-663277

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005104 IEA fibroblast growth factor receptor binding
GO:0005515 IEA protein binding
GO:0005576 TAS extracellular region
GO:0005615 NAS extracellular space
GO:0005730 IEA nucleolus
GO:0005794 IEA Golgi apparatus
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0008083 IEA growth factor activity
GO:0008286 TAS insulin receptor signaling pathway
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0009986 IEA cell surface
GO:0030154 NAS cell differentiation
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0045087 TAS innate immune response
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056074 fgf22 fibroblast growth factor 22 protein_coding Danio_rerio
ENSDARG00000076510 fgf22 fibroblast growth factor 22 protein_coding Danio_rerio
ENSMUSG00000020327 Fgf22 fibroblast growth factor 22 protein_coding Mus_musculus

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