C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: follistatin-like 3 (secreted glycoprotein)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000070404 FSTL3 9606 + 19:676365-683390 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000166139 FSTL3-001 676365-683390 protein_coding
  ENST00000588773 FSTL3-007 680715-682054 protein_coding
  ENST00000589185 FSTL3-005 680034-681413 protein_coding
  ENST00000591552 FSTL3-003 677942-682046 protein_coding
  ENST00000591573 FSTL3-008 680751-681771 protein_coding
  ENST00000592058 FSTL3-006 678061-682054 processed_transcript
  ENST00000592947 FSTL3-002 680715-682205 protein_coding
  ENST00000605925 FSTL3-004 680751-682050 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000166139ENST00000588773ENST00000589185ENST00000592058ENST00000592947ENST00000605925
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000166139 8.189±0.00 8.213±0.00 0.082±0.00 N/A 0.998±0.00 5.538±0.00 4.636±4.40 9.191±0.00 2.204±0.21 21.425±21.00 1.056±0.00 15.106±20.39 208.529±155.39 8.077±3.72
ENST00000588773 N/A N/A 0.615±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000589185 N/A N/A N/A N/A N/A N/A N/A 2.615±0.00 N/A N/A N/A N/A N/A N/A
ENST00000592058 N/A N/A N/A 4.214±0.00 N/A N/A 4.170±2.51 N/A N/A N/A N/A N/A N/A N/A
ENST00000592947 N/A N/A N/A 0.147±0.00 N/A 0.713±0.00 0.577±0.00 N/A 1.784±0.00 N/A N/A N/A N/A N/A
ENST00000605925 N/A N/A 0.244±0.00 0.806±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008XG CIL_0008XG_0001 VISTA 19:477571-1083531
CIL_0004VK CIL_0004VK_0001 CGP 19:647526-683390
CIL_00008F CIL_00008F_0001 CGP 19:676365-695498

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001503 IEA ossification
GO:0001822 IEA kidney development
GO:0001968 IPI fibronectin binding
GO:0002244 IDA hematopoietic progenitor cell differentiation
GO:0005515 IPI:IEA protein binding
GO:0005576 TAS extracellular region
GO:0005615 IDA extracellular space
GO:0005634 IDA nucleus
GO:0005794 IEA Golgi apparatus
GO:0006351 IEA transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0007283 IEA spermatogenesis
GO:0008584 IEA male gonad development
GO:0022409 IDA positive regulation of cell-cell adhesion
GO:0030141 IEA secretory granule
GO:0030324 IEA lung development
GO:0030325 IEA adrenal gland development
GO:0030514 IDA negative regulation of BMP signaling pathway
GO:0032926 IDA negative regulation of activin receptor signaling pathway
GO:0044306 IEA neuron projection terminus
GO:0045671 IDA negative regulation of osteoclast differentiation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048185 IPI activin binding
GO:0071248 IEA cellular response to metal ion
GO:0090101 IDA negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000025670 fstl3 follistatin-like 3 (secreted glycoprotein) protein_coding Danio_rerio
ENSMUSG00000020325 Fstl3 follistatin-like 3 protein_coding Mus_musculus

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