C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ring finger protein 126
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000070423 RNF126 9606 - 19:647526-663277 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000292363 RNF126-001 647530-663277 protein_coding
  ENST00000586749 RNF126-003 647530-650594 retained_intron
  ENST00000589762 RNF126-008 648132-663233 protein_coding
  ENST00000590885 RNF126-006 647526-661402 processed_transcript
  ENST00000591394 RNF126-002 651385-663184 retained_intron
  ENST00000592626 RNF126-004 652358-663174 retained_intron
  ENST00000605891 RNF126-007 647526-663194 nonsense_mediated_decay
  ENST00000606702 RNF126-005 650292-663161 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000292363ENST00000586749ENST00000589762ENST00000590885ENST00000591394ENST00000592626ENST00000605891ENST00000606702
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000292363 15.536±0.00 19.972±0.00 N/A N/A 5.369±4.29 4.164±2.03 12.578±0.00 7.310±0.00 15.652±0.00 4.242±3.98 32.028±0.00 10.575±6.33 12.382±1.64 37.534±14.66
ENST00000586749 N/A 5.573±0.00 N/A N/A N/A 0.798±0.36 N/A 1.562±0.00 0.190±0.00 4.596±0.00 N/A 1.190±0.97 N/A N/A
ENST00000589762 5.700±0.00 13.799±0.00 N/A 8.805±0.00 12.372±0.00 3.823±0.00 N/A N/A 4.470±4.17 12.345±0.00 16.158±0.00 7.985±6.01 6.057±0.58 24.153±0.00
ENST00000590885 3.509±0.00 10.240±0.00 N/A N/A 7.438±0.00 N/A N/A N/A N/A N/A 9.264±0.00 N/A N/A 13.285±0.00
ENST00000591394 N/A N/A 0.333±0.00 N/A N/A N/A N/A N/A N/A 0.190±0.00 N/A 0.961±0.00 N/A N/A
ENST00000592626 N/A N/A N/A N/A 1.282±0.00 N/A N/A N/A N/A N/A N/A 0.447±0.00 N/A N/A
ENST00000605891 N/A N/A N/A N/A N/A N/A N/A 3.049±0.00 0.163±0.00 N/A N/A 15.615±0.00 N/A N/A
ENST00000606702 17.672±0.00 N/A N/A 29.852±0.00 0.992±0.00 10.937±0.00 0.577±0.00 N/A N/A N/A 2.037±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008XG CIL_0008XG_0001 VISTA 19:477571-1083531
CIL_00008H CIL_00008H_0001 CGP 19:639879-663277
CIL_0004VK CIL_0004VK_0001 CGP 19:647526-683390

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005154 IEA epidermal growth factor receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006513 IDA protein monoubiquitination
GO:0008270 IEA zinc ion binding
GO:0016874 IEA ligase activity
GO:0032880 IMP regulation of protein localization
GO:0042059 IMP negative regulation of epidermal growth factor receptor signaling pathway
GO:0042127 IMP regulation of cell proliferation
GO:0042147 IMP retrograde transport, endosome to Golgi
GO:0042787 IMP protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043161 IDA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043162 IMP ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0046872 IEA metal ion binding
GO:0061630 IDA ubiquitin protein ligase activity
GO:0070534 ISS protein K63-linked ubiquitination
GO:0070936 ISS protein K48-linked ubiquitination

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078306 CU570683.1 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000088454 rnf126 ring finger protein 126 protein_coding Danio_rerio
ENSMUSG00000035890 Rnf126 ring finger protein 126 protein_coding Mus_musculus

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