C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: polymerase (DNA directed), beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000070501 POLB 9606 + 8:42338454-42371808 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265421 POLB-001 42338455-42371808 protein_coding
  ENST00000517393 POLB-011 42361298-42371808 protein_coding
  ENST00000518579 POLB-016 42357174-42371752 protein_coding
  ENST00000518925 POLB-005 42338482-42369297 protein_coding
  ENST00000519094 POLB-003 42338494-42339380 retained_intron
  ENST00000519524 POLB-010 42355459-42361712 retained_intron
  ENST00000519771 POLB-014 42338605-42369329 nonsense_mediated_decay
  ENST00000520008 POLB-002 42338459-42361361 protein_coding
  ENST00000521290 POLB-008 42349039-42371808 protein_coding
  ENST00000521418 POLB-013 42369607-42371808 retained_intron
  ENST00000521492 POLB-012 42368936-42371808 protein_coding
  ENST00000522297 POLB-004 42338494-42349289 retained_intron
  ENST00000522610 POLB-015 42338507-42371765 nonsense_mediated_decay
  ENST00000523465 POLB-009 42357198-42357942 retained_intron
  ENST00000524208 POLB-007 42344960-42369988 nonsense_mediated_decay
  ENST00000530566 POLB-018 42338494-42340147 processed_transcript
  ENST00000532157 POLB-006 42338454-42357203 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000265421ENST00000518925ENST00000519094ENST00000519771ENST00000520008ENST00000521290ENST00000521418ENST00000521492ENST00000522297ENST00000522610ENST00000523465ENST00000524208ENST00000530566ENST00000532157
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000265421 1.261±0.00 3.266±0.00 N/A 4.373±3.24 2.067±0.15 3.087±0.00 3.858±2.97 3.193±0.00 3.501±2.47 2.421±0.00 5.664±0.00 5.405±2.89 3.786±1.12 21.604±10.19
ENST00000518925 N/A N/A N/A N/A N/A N/A N/A N/A 1.163±0.00 N/A N/A N/A N/A N/A
ENST00000519094 N/A N/A 0.783±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000519771 1.902±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000520008 N/A N/A 0.838±0.00 2.910±0.00 2.497±0.00 0.451±0.00 3.296±0.00 N/A 2.064±0.00 4.044±0.00 N/A 5.514±2.03 3.938±0.00 18.828±0.00
ENST00000521290 1.591±0.00 N/A N/A 1.945±0.00 N/A N/A N/A 2.499±0.00 N/A 2.259±0.12 N/A 2.120±0.00 N/A 9.942±0.00
ENST00000521418 N/A N/A 0.620±0.00 N/A N/A 1.025±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000521492 N/A N/A N/A N/A N/A 1.020±0.00 N/A N/A N/A 1.805±0.00 N/A N/A N/A N/A
ENST00000522297 N/A N/A N/A N/A N/A 0.749±0.00 N/A N/A N/A 2.563±0.00 4.237±0.00 N/A N/A N/A
ENST00000522610 N/A 1.618±0.00 N/A 0.833±0.00 N/A N/A 0.272±0.00 N/A 0.902±0.00 N/A N/A N/A N/A 4.124±0.00
ENST00000523465 N/A N/A 1.034±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000524208 N/A N/A N/A N/A N/A N/A 0.613±0.00 1.716±0.00 N/A 3.551±0.00 4.182±0.00 1.677±0.00 N/A N/A
ENST00000530566 N/A N/A N/A N/A N/A N/A N/A 4.462±0.00 N/A N/A N/A N/A N/A N/A
ENST00000532157 N/A N/A N/A N/A 2.955±0.00 0.420±0.00 0.676±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003684 IEA damaged DNA binding
GO:0003887 IDA:IEA DNA-directed DNA polymerase activity
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005874 IDA microtubule
GO:0005876 IDA spindle microtubule
GO:0006261 TAS DNA-dependent DNA replication
GO:0006281 TAS:IEA DNA repair
GO:0006284 IDA base-excision repair
GO:0006287 IEA base-excision repair, gap-filling
GO:0006290 IEA pyrimidine dimer repair
GO:0006974 IMP cellular response to DNA damage stimulus
GO:0008017 IDA microtubule binding
GO:0008630 IEA intrinsic apoptotic signaling pathway in response to DNA damage
GO:0016829 IDA lyase activity
GO:0019899 IPI enzyme binding
GO:0034061 IEA DNA polymerase activity
GO:0045471 IEA response to ethanol
GO:0046872 IEA metal ion binding
GO:0051402 IEA neuron apoptotic process
GO:0071897 IEA DNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003749 polb polymerase (DNA directed), beta protein_coding Danio_rerio
ENSMUSG00000031536 Polb polymerase (DNA directed), beta protein_coding Mus_musculus

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