C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATPase, H+ transporting, lysosomal accessory protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000071553 ATP6AP1 9606 + X:154428632-154436516 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000369762 ATP6AP1-001 154428632-154436516 protein_coding
  ENST00000422890 ATP6AP1-003 154428645-154435379 protein_coding
  ENST00000429585 ATP6AP1-006 154428741-154435379 nonsense_mediated_decay
  ENST00000439372 ATP6AP1-007 154428687-154431600 nonsense_mediated_decay
  ENST00000446552 ATP6AP1-008 154428689-154431879 nonsense_mediated_decay
  ENST00000449556 ATP6AP1-010 154428663-154434219 protein_coding
  ENST00000455205 ATP6AP1-002 154428698-154436515 nonsense_mediated_decay
  ENST00000484908 ATP6AP1-009 154431722-154434269 processed_transcript
  ENST00000491569 ATP6AP1-004 154428845-154436515 retained_intron
  ENST00000619046 ATP6AP1-201 154430584-154436515 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000369762ENST00000455205ENST00000484908ENST00000491569
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000369762 26.235±0.00 13.642±0.00 1.979±0.00 44.212±31.45 20.748±17.87 11.031±9.13 19.002±18.06 36.849±33.81 10.384±7.07 46.132±42.09 23.183±0.00 32.670±26.68 86.374±43.81 29.060±0.00
ENST00000455205 N/A 2.518±0.00 N/A N/A N/A 0.204±0.00 N/A 0.488±0.00 0.252±0.00 N/A N/A N/A N/A N/A
ENST00000484908 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.201±0.00 N/A N/A N/A
ENST00000491569 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.724±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001L3 CIL_0001L3_0001 CGP X:154411518-154436516
CIL_0001L4 CIL_0001L4_0001 CGP X:154428632-154443467

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005215 TAS transporter activity
GO:0005524 IEA ATP binding
GO:0005773 IEA vacuole
GO:0015991 IEA ATP hydrolysis coupled proton transport
GO:0015992 TAS proton transport
GO:0016021 IEA integral component of membrane
GO:0016469 TAS proton-transporting two-sector ATPase complex
GO:0017137 ISS Rab GTPase binding
GO:0033180 IEA proton-transporting V-type ATPase, V1 domain
GO:0045669 ISS positive regulation of osteoblast differentiation
GO:0045780 ISS positive regulation of bone resorption
GO:0045851 ISS pH reduction
GO:0045921 ISS positive regulation of exocytosis
GO:0046933 IEA proton-transporting ATP synthase activity, rotational mechanism
GO:0046961 IEA proton-transporting ATPase activity, rotational mechanism
GO:0051656 ISS establishment of organelle localization
GO:0070062 IDA extracellular vesicular exosome
GO:0070374 ISS positive regulation of ERK1 and ERK2 cascade
GO:2001206 ISS positive regulation of osteoclast development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037153 atp6ap1b ATPase, H+ transporting, lysosomal accessory protein 1b protein_coding Danio_rerio
ENSDARG00000041417 atp6ap1a ATPase, H+ transporting, lysosomal accessory protein 1a protein_coding Danio_rerio
ENSMUSG00000019087 Atp6ap1 ATPase, H+ transporting, lysosomal accessory protein 1 protein_coding Mus_musculus

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