C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: monoglyceride lipase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000074416 MGLL 9606 - 3:127689062-127823250 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265052 MGLL-201 127689062-127822882 protein_coding
  ENST00000398101 MGLL-004 127692117-127736357 protein_coding
  ENST00000398104 MGLL-202 127689062-127823250 protein_coding
  ENST00000434178 MGLL-001 127689066-127823185 protein_coding
  ENST00000453507 MGLL-203 127689062-127822882 protein_coding
  ENST00000465597 MGLL-007 127710620-127799464 processed_transcript
  ENST00000476654 MGLL-008 127722550-127791261 processed_transcript
  ENST00000476682 MGLL-003 127692112-127714146 processed_transcript
  ENST00000479967 MGLL-002 127715474-127823185 processed_transcript
  ENST00000484451 MGLL-010 127692139-127722570 protein_coding
  ENST00000487473 MGLL-011 127692117-127722570 protein_coding
  ENST00000493611 MGLL-005 127721076-127784008 protein_coding
  ENST00000494830 MGLL-006 127781789-127822143 protein_coding
  ENST00000496306 MGLL-009 127692111-127721171 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000265052ENST00000398101ENST00000398104ENST00000434178ENST00000453507ENST00000476682ENST00000484451ENST00000496306
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000265052 N/A 2.393±0.00 0.788±0.00 3.359±0.00 4.670±0.00 N/A 1.035±0.00 2.431±0.00 N/A 1.411±0.00 0.635±0.00 N/A N/A N/A
ENST00000398101 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.171±0.00 N/A N/A N/A
ENST00000398104 88.135±0.00 15.259±0.00 1.037±0.00 11.543±9.00 152.167±0.00 20.108±16.37 15.123±13.82 17.318±12.53 15.593±14.56 16.199±14.88 11.935±0.00 8.239±3.06 31.212±4.15 7.898±5.91
ENST00000434178 N/A N/A N/A N/A N/A N/A N/A N/A 0.829±0.00 N/A N/A 0.507±0.00 N/A N/A
ENST00000453507 N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.833±0.00 N/A N/A N/A N/A
ENST00000476682 N/A N/A N/A N/A N/A 5.246±0.00 N/A N/A 0.639±0.00 0.959±0.00 N/A N/A N/A N/A
ENST00000484451 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 13.045±9.16 42.889±0.00 N/A
ENST00000496306 N/A N/A N/A 12.112±0.00 N/A N/A N/A N/A 6.283±0.00 N/A N/A 2.811±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004622 TAS lysophospholipase activity
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005886 TAS plasma membrane
GO:0006629 TAS:IEA lipid metabolic process
GO:0006633 IEA fatty acid biosynthetic process
GO:0006644 TAS phospholipid metabolic process
GO:0006954 TAS inflammatory response
GO:0007596 TAS blood coagulation
GO:0008152 IEA metabolic process
GO:0008289 IEA lipid binding
GO:0009966 ISS regulation of signal transduction
GO:0016787 IEA hydrolase activity
GO:0019369 ISS arachidonic acid metabolic process
GO:0019433 IEA triglyceride catabolic process
GO:0030168 TAS platelet activation
GO:0030424 IEA axon
GO:0030516 IEA regulation of axon extension
GO:0036155 TAS acylglycerol acyl-chain remodeling
GO:0042803 IPI protein homodimerization activity
GO:0043196 IEA varicosity
GO:0044281 TAS small molecule metabolic process
GO:0045202 IEA synapse
GO:0046464 ISS acylglycerol catabolic process
GO:0046474 TAS glycerophospholipid biosynthetic process
GO:0047372 ISS acylglycerol lipase activity
GO:0050727 ISS regulation of inflammatory response
GO:0051930 ISS regulation of sensory perception of pain
GO:0060292 IEA long term synaptic depression
GO:2000124 ISS regulation of endocannabinoid signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036820 mgll monoglyceride lipase protein_coding Danio_rerio
ENSMUSG00000033174 Mgll monoglyceride lipase protein_coding Mus_musculus

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