C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein tyrosine phosphatase-like A domain containing 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000074696 PTPLAD1 9606 + 15:65530418-65578352 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261875 PTPLAD1-001 65530466-65578352 protein_coding
  ENST00000442729 PTPLAD1-011 65530482-65576637 protein_coding
  ENST00000561763 PTPLAD1-012 65574265-65576499 processed_transcript
  ENST00000562832 PTPLAD1-009 65551026-65570199 protein_coding
  ENST00000562901 PTPLAD1-003 65530418-65576673 protein_coding
  ENST00000565299 PTPLAD1-004 65530490-65576499 protein_coding
  ENST00000566074 PTPLAD1-006 65530754-65576955 protein_coding
  ENST00000566239 PTPLAD1-010 65530588-65551937 retained_intron
  ENST00000566511 PTPLAD1-007 65531260-65576977 protein_coding
  ENST00000568793 PTPLAD1-005 65530505-65577062 protein_coding
  ENST00000569894 PTPLAD1-008 65550819-65576726 protein_coding
  ENST00000624437 PTPLAD1-013 65564222-65566967 TEC

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000261875ENST00000442729ENST00000566074ENST00000568793ENST00000569894
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000261875 7.107±0.00 8.585±0.00 9.463±0.00 35.422±5.94 10.840±0.92 9.373±2.09 1.752±0.64 27.484±7.02 14.518±2.99 6.089±0.72 1.454±0.00 24.406±4.97 18.216±1.44 18.246±5.28
ENST00000442729 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.872±0.00 N/A N/A N/A
ENST00000566074 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 12.334±0.00 8.913±0.00 11.359±0.00
ENST00000568793 N/A N/A N/A N/A N/A 2.184±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000569894 N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.573±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006F6 CIL_0006F6_0002 CGP 15:65530418-65611289

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005096 TAS GTPase activator activity
GO:0005515 IPI protein binding
GO:0005783 IEA endoplasmic reticulum
GO:0005925 IDA focal adhesion
GO:0006633 IEA fatty acid biosynthetic process
GO:0007249 IEA I-kappaB kinase/NF-kappaB signaling
GO:0007254 IEA JNK cascade
GO:0007257 TAS activation of JUN kinase activity
GO:0007264 TAS small GTPase mediated signal transduction
GO:0007266 IEA Rho protein signal transduction
GO:0016021 IEA integral component of membrane
GO:0016601 NAS Rac protein signal transduction
GO:0016829 IEA lyase activity
GO:0043547 TAS positive regulation of GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016038 ptplad1 protein tyrosine phosphatase-like A domain containing 1 protein_coding Danio_rerio
ENSMUSG00000033629 Ptplad1 protein tyrosine phosphatase-like A domain containing 1 protein_coding Mus_musculus

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