C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phospholipase D1, phosphatidylcholine-specific
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000075651 PLD1 9606 - 3:171600405-171810950 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000331659 PLD1-201 171791790-171809924 protein_coding
  ENST00000351298 PLD1-001 171600826-171810494 protein_coding
  ENST00000356327 PLD1-002 171600405-171810438 protein_coding
  ENST00000418087 PLD1-010 171735501-171771359 protein_coding
  ENST00000440204 PLD1-011 171726004-171810462 nonsense_mediated_decay
  ENST00000446289 PLD1-003 171611466-171674516 protein_coding
  ENST00000460926 PLD1-007 171788567-171810441 processed_transcript
  ENST00000463281 PLD1-017 171600405-171602338 processed_transcript
  ENST00000465816 PLD1-014 171612279-171666305 processed_transcript
  ENST00000467432 PLD1-015 171612307-171643154 retained_intron
  ENST00000471075 PLD1-004 171653242-171677853 retained_intron
  ENST00000475273 PLD1-016 171721354-171737932 processed_transcript
  ENST00000481505 PLD1-013 171688695-171708870 retained_intron
  ENST00000489995 PLD1-009 171765129-171771385 processed_transcript
  ENST00000497307 PLD1-006 171788581-171810950 processed_transcript
  ENST00000498278 PLD1-012 171713878-171810437 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000331659ENST00000351298ENST00000356327ENST00000440204ENST00000460926ENST00000465816
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000331659 0.096±0.00 0.143±0.00 0.076±0.00 0.155±0.02 0.784±0.77 0.564±0.51 0.024±0.00 0.016±0.00 0.222±0.00 0.150±0.00 N/A 0.380±0.26 0.042±0.04 0.101±0.06
ENST00000351298 3.061±0.00 1.528±0.00 N/A 1.537±0.52 1.927±0.67 2.020±0.35 3.809±1.75 2.641±1.55 1.313±0.64 1.416±0.06 0.185±0.15 2.237±1.05 1.612±0.23 1.528±1.10
ENST00000356327 1.005±0.00 N/A N/A 0.671±0.31 3.601±0.00 0.893±0.00 N/A N/A N/A N/A N/A 1.954±1.25 1.147±0.31 0.911±0.00
ENST00000440204 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.101±0.00 N/A N/A N/A
ENST00000460926 N/A N/A N/A 2.974±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000465816 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.492±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007SJ CIL_0007SJ_0001 VISTA 3:171005102-171609864
CIL_00049S CIL_00049S_0002 CGP 3:171061339-171810950

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004630 IEA phospholipase D activity
GO:0005515 IPI protein binding
GO:0005765 IDA lysosomal membrane
GO:0005768 IDA endosome
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005794 IDA Golgi apparatus
GO:0006644 TAS phospholipid metabolic process
GO:0006654 TAS phosphatidic acid biosynthetic process
GO:0006655 TAS phosphatidylglycerol biosynthetic process
GO:0006935 TAS chemotaxis
GO:0007264 TAS small GTPase mediated signal transduction
GO:0007265 TAS Ras protein signal transduction
GO:0008152 IEA metabolic process
GO:0016020 IDA membrane
GO:0016042 IEA lipid catabolic process
GO:0035091 IEA phosphatidylinositol binding
GO:0044281 TAS small molecule metabolic process
GO:0046474 TAS glycerophospholipid biosynthetic process
GO:0050830 IEA defense response to Gram-positive bacterium
GO:0070290 IEA N-acylphosphatidylethanolamine-specific phospholipase D activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056228 pld1a phospholipase D1a protein_coding Danio_rerio
ENSDARG00000057125 pld1b phospholipase D1b protein_coding Danio_rerio
ENSMUSG00000027695 Pld1 phospholipase D1 protein_coding Mus_musculus

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