C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein phosphatase 2, regulatory subunit B', gamma
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000078304 PPP2R5C 9606 + 14:101761798-101927989 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000328724 PPP2R5C-002 101761885-101927685 protein_coding
  ENST00000334743 PPP2R5C-001 101809895-101927977 protein_coding
  ENST00000350249 PPP2R5C-005 101809803-101927519 protein_coding
  ENST00000422945 PPP2R5C-201 101761798-101927989 protein_coding
  ENST00000445439 PPP2R5C-006 101809895-101912625 protein_coding
  ENST00000553554 PPP2R5C-016 101786111-101797701 protein_coding
  ENST00000553730 PPP2R5C-008 101809866-101883016 retained_intron
  ENST00000553842 PPP2R5C-021 101823878-101836525 processed_transcript
  ENST00000553890 PPP2R5C-028 101762928-101836451 protein_coding
  ENST00000554137 PPP2R5C-027 101882161-101894517 nonsense_mediated_decay
  ENST00000554147 PPP2R5C-025 101917769-101925449 retained_intron
  ENST00000554442 PPP2R5C-007 101761862-101836573 protein_coding
  ENST00000554504 PPP2R5C-018 101762905-101824229 processed_transcript
  ENST00000555237 PPP2R5C-024 101906505-101921382 protein_coding
  ENST00000556068 PPP2R5C-004 101761862-101821098 processed_transcript
  ENST00000556086 PPP2R5C-015 101786121-101789896 processed_transcript
  ENST00000556218 PPP2R5C-012 101882205-101912600 processed_transcript
  ENST00000556260 PPP2R5C-014 101761870-101767049 protein_coding
  ENST00000556307 PPP2R5C-019 101809837-101882205 nonsense_mediated_decay
  ENST00000556373 PPP2R5C-022 101824838-101856885 processed_transcript
  ENST00000556493 PPP2R5C-020 101823653-101856757 processed_transcript
  ENST00000556570 PPP2R5C-029 101879222-101883562 processed_transcript
  ENST00000556805 PPP2R5C-011 101889793-101893053 retained_intron
  ENST00000556946 PPP2R5C-017 101809835-101836701 protein_coding
  ENST00000557071 PPP2R5C-023 101909648-101925307 nonsense_mediated_decay
  ENST00000557095 PPP2R5C-009 101809905-101906647 protein_coding
  ENST00000557268 PPP2R5C-003 101761900-101925623 protein_coding
  ENST00000557534 PPP2R5C-010 101883302-101901744 nonsense_mediated_decay
  ENST00000557621 PPP2R5C-026 101809834-101893053 protein_coding
  ENST00000557714 PPP2R5C-030 101809869-101836432 protein_coding
  ENST00000557716 PPP2R5C-013 101883537-101912625 protein_coding
  ENST00000561006 PPP2R5C-031 101901857-101912624 protein_coding
  ENST00000607042 PPP2R5C-032 101824162-101824478 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000328724ENST00000334743ENST00000350249ENST00000422945ENST00000445439ENST00000556068ENST00000556260ENST00000557095ENST00000557268
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000328724 7.081±0.00 8.467±0.00 3.419±0.00 8.038±2.68 6.772±0.11 8.041±3.24 7.513±4.58 4.698±1.54 4.018±0.59 7.793±2.30 5.365±1.88 6.762±1.97 4.598±0.45 13.976±1.38
ENST00000334743 4.066±0.00 5.825±0.00 N/A 7.356±0.00 4.993±0.00 8.763±0.00 4.236±2.26 3.769±0.00 2.157±0.00 3.571±0.26 2.057±0.00 6.742±1.02 2.927±0.02 9.354±0.00
ENST00000350249 4.183±0.00 4.667±0.00 N/A N/A N/A N/A 5.251±0.00 2.618±0.00 N/A N/A N/A N/A 1.440±0.00 N/A
ENST00000422945 N/A N/A N/A N/A N/A 2.711±0.00 N/A N/A 1.972±0.00 N/A N/A N/A N/A N/A
ENST00000445439 N/A N/A N/A N/A 10.681±0.00 N/A 4.787±0.00 2.785±0.00 4.369±0.00 8.493±0.23 N/A 4.065±0.00 5.062±1.70 N/A
ENST00000556068 N/A N/A N/A N/A N/A 3.800±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000556260 15.265±0.00 11.576±0.00 N/A 9.496±1.39 10.452±2.40 6.381±0.00 8.793±0.00 4.592±0.85 5.087±0.73 7.045±0.00 3.055±0.00 4.961±0.78 3.732±0.00 9.471±0.40
ENST00000557095 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.809±0.00 N/A N/A N/A
ENST00000557268 N/A N/A 3.466±0.00 N/A N/A N/A 3.326±0.00 2.364±0.00 4.193±0.00 N/A N/A 7.243±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004A7 CIL_0004A7_0001 CGP 14:101561351-101927989
CIL_0004A6 CIL_0004A6_0001 CGP 14:101761798-102050792

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000159 IDA:IEA protein phosphatase type 2A complex
GO:0000775 IDA chromosome, centromeric region
GO:0005488 IEA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006508 IDA proteolysis
GO:0006977 IDA DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007165 NAS:IEA signal transduction
GO:0008233 IDA peptidase activity
GO:0008285 IDA negative regulation of cell proliferation
GO:0008601 IDA:IEA protein phosphatase type 2A regulator activity
GO:0016021 IDA integral component of membrane
GO:0016485 IDA protein processing
GO:0042771 IMP intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043161 IMP proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0050790 IEA regulation of catalytic activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031200 ppp2r5cb protein phosphatase 2, regulatory subunit B', gamma b protein_coding Danio_rerio
ENSDARG00000059083 PPP2R5C (2 of 2) protein phosphatase 2, regulatory subunit B', gamma protein_coding Danio_rerio
ENSMUSG00000017843 Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma protein_coding Mus_musculus

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