C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nardilysin (N-arginine dibasic convertase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000078618 NRD1 9606 - 1:51789191-51878937 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000352171 NRD1-001 51789191-51878805 protein_coding
  ENST00000354831 NRD1-002 51789191-51878805 protein_coding
  ENST00000440943 NRD1-003 51789191-51814071 protein_coding
  ENST00000464385 NRD1-010 51789217-51789822 processed_transcript
  ENST00000468722 NRD1-006 51862114-51878723 processed_transcript
  ENST00000473805 NRD1-012 51815929-51834073 processed_transcript
  ENST00000475310 NRD1-011 51794472-51795708 processed_transcript
  ENST00000475715 NRD1-013 51825297-51837572 processed_transcript
  ENST00000483007 NRD1-007 51810291-51814625 processed_transcript
  ENST00000485608 NRD1-004 51789212-51840454 processed_transcript
  ENST00000491410 NRD1-005 51839992-51878771 processed_transcript
  ENST00000497358 NRD1-008 51794472-51801094 processed_transcript
  ENST00000539524 NRD1-201 51789196-51878040 protein_coding
  ENST00000544028 NRD1-202 51789196-51878937 protein_coding
  ENST00000615102 NRD1-203 51789212-51878710 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000352171ENST00000354831ENST00000485608ENST00000491410ENST00000615102
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000352171 11.239±0.00 N/A 4.613±0.00 14.305±0.00 N/A 12.991±0.00 N/A N/A N/A N/A N/A 11.695±5.26 12.309±1.64 N/A
ENST00000354831 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 38.869±0.00 N/A N/A 37.942±2.03
ENST00000485608 N/A N/A N/A 5.252±0.00 4.877±0.00 N/A 4.192±0.00 13.512±0.00 N/A 7.779±0.00 33.557±0.00 4.398±0.00 N/A N/A
ENST00000491410 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 11.185±0.00 N/A N/A
ENST00000615102 24.217±0.00 39.586±0.00 N/A 15.286±10.08 18.356±13.70 12.670±4.41 25.861±22.23 15.213±6.00 16.445±8.47 12.199±0.00 131.965±0.00 13.088±0.81 18.535±14.26 35.589±1.51

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004222 NAS metalloendopeptidase activity
GO:0005515 IPI protein binding
GO:0005739 IEA mitochondrion
GO:0005829 TAS cytosol
GO:0006508 NAS proteolysis
GO:0007528 TAS neuromuscular junction development
GO:0008283 TAS cell proliferation
GO:0009986 TAS cell surface
GO:0016477 TAS cell migration
GO:0046872 IEA metal ion binding
GO:0048408 TAS epidermal growth factor binding
GO:0051044 IDA positive regulation of membrane protein ectodomain proteolysis
GO:0052548 IDA regulation of endopeptidase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019596 NRD1 (1 of 2) nardilysin (N-arginine dibasic convertase) protein_coding Danio_rerio
ENSDARG00000062372 nrd1 nardilysin (N-arginine dibasic convertase) protein_coding Danio_rerio
ENSMUSG00000053510 Nrd1 nardilysin, N-arginine dibasic convertase, NRD convertase 1 protein_coding Mus_musculus

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