C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sestrin 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000080546 SESN1 9606 - 6:108986437-109094819 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000302071 SESN1-003 108986442-109008988 protein_coding
  ENST00000356644 SESN1-002 108986442-109009555 protein_coding
  ENST00000368971 SESN1-006 108992819-108998875 retained_intron
  ENST00000436639 SESN1-001 108986437-109094819 protein_coding
  ENST00000517548 SESN1-004 109088102-109093968 processed_transcript
  ENST00000520364 SESN1-007 108988363-108993016 retained_intron
  ENST00000523632 SESN1-005 108999939-109001472 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000356644ENST00000436639
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000356644 7.224±0.00 4.032±0.00 N/A 7.720±1.19 2.639±1.29 10.218±0.00 4.483±1.59 4.775±0.00 2.699±1.09 5.165±2.20 12.217±0.00 12.860±6.94 16.466±8.42 9.928±1.82
ENST00000436639 2.657±0.00 1.735±0.00 1.204±0.00 5.606±0.00 3.196±0.96 2.094±0.27 8.334±0.00 2.206±0.91 1.351±0.53 2.387±0.08 13.573±7.49 4.338±0.31 4.607±0.75 6.629±2.10

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005634 IEA nucleus
GO:0006974 TAS cellular response to DNA damage stimulus
GO:0007050 TAS cell cycle arrest
GO:0008285 TAS negative regulation of cell proliferation
GO:0051896 IEA regulation of protein kinase B signaling
GO:1901031 IEA regulation of response to reactive oxygen species

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020693 sesn1 sestrin 1 protein_coding Danio_rerio
ENSMUSG00000038332 Sesn1 sestrin 1 protein_coding Mus_musculus

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