C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NDC80 kinetochore complex component
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000080986 NDC80 9606 + 18:2571511-2616635 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261597 NDC80-001 2571511-2616635 protein_coding
  ENST00000574096 NDC80-017 2610781-2615314 protein_coding
  ENST00000574567 NDC80-016 2578123-2579196 retained_intron
  ENST00000575515 NDC80-011 2571565-2577869 protein_coding
  ENST00000576274 NDC80-013 2577849-2582879 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000261597ENST00000574096ENST00000575515ENST00000576274
Transcript ID Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000261597 0.160±0.00 0.023±0.01 N/A 1.100±0.00 N/A 0.154±0.00 0.107±0.08 0.028±0.00 N/A 13.522±14.27 5.871±5.26 18.185±10.99
ENST00000574096 N/A N/A N/A N/A N/A N/A N/A 0.434±0.00 N/A N/A N/A N/A
ENST00000575515 N/A 0.207±0.00 N/A N/A N/A N/A 0.192±0.00 N/A N/A N/A N/A N/A
ENST00000576274 0.320±0.00 0.162±0.00 0.508±0.00 0.093±0.00 0.107±0.05 0.117±0.00 0.051±0.00 N/A 0.008±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000070 TAS mitotic sister chromatid segregation
GO:0000132 IMP establishment of mitotic spindle orientation
GO:0000278 TAS mitotic cell cycle
GO:0000775 TAS chromosome, centromeric region
GO:0000776 IDA kinetochore
GO:0000777 IDA condensed chromosome kinetochore
GO:0000942 IDA condensed nuclear chromosome outer kinetochore
GO:0005515 IPI protein binding
GO:0005634 TAS nucleus
GO:0005829 TAS cytosol
GO:0007052 IMP mitotic spindle organization
GO:0007059 IMP chromosome segregation
GO:0007067 TAS mitotic nuclear division
GO:0008608 IMP attachment of spindle microtubules to kinetochore
GO:0016020 IDA:IEA membrane
GO:0016192 IEA vesicle-mediated transport
GO:0031262 IDA Ndc80 complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000071694 ndc80 NDC80 homolog, kinetochore complex component (S. cerevisiae) protein_coding Danio_rerio
ENSMUSG00000024056 Ndc80 NDC80 homolog, kinetochore complex component (S. cerevisiae) protein_coding Mus_musculus

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