C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: PH domain and leucine rich repeat protein phosphatase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000081913 PHLPP1 9606 + 18:62715450-62980433 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262719 PHLPP1-001 62715450-62980433 protein_coding
  ENST00000487409 PHLPP1-002 62832174-62895088 processed_transcript
  ENST00000497351 PHLPP1-003 62779399-62860513 processed_transcript
  ENST00000588452 PHLPP1-005 62832160-62889665 processed_transcript
  ENST00000588953 PHLPP1-006 62837678-62839875 processed_transcript
  ENST00000591106 PHLPP1-007 62906287-62941910 processed_transcript
  ENST00000591386 PHLPP1-004 62903150-62958726 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000262719ENST00000497351ENST00000588953
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000262719 2.742±0.00 0.477±0.00 0.345±0.00 7.832±4.02 1.490±0.49 1.853±0.15 0.598±0.32 1.267±0.10 1.760±0.08 0.822±0.37 2.717±0.00 1.520±0.58 2.683±0.30 4.609±2.26
ENST00000497351 N/A N/A 3.404±0.00 N/A N/A N/A 0.592±0.00 5.843±0.00 3.643±0.00 N/A 1.670±0.00 N/A N/A N/A
ENST00000588953 N/A 0.235±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00076H CIL_00076H_0001 CGP 18:62523007-62980433
CIL_00076I CIL_00076I_0001 CGP 18:62715450-63320128

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004721 IEA phosphoprotein phosphatase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IEA nucleus
GO:0005829 TAS cytosol
GO:0006915 IEA apoptotic process
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0009649 IEA entrainment of circadian clock
GO:0016020 IEA membrane
GO:0016311 IEA dephosphorylation
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0045087 TAS innate immune response
GO:0046872 IEA metal ion binding
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078694 PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 protein_coding Danio_rerio
ENSMUSG00000044340 Phlpp1 PH domain and leucine rich repeat protein phosphatase 1 protein_coding Mus_musculus

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