C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: STE20-related kinase adaptor beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000082146 STRADB 9606 + 2:201387858-201480846 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000194530 STRADB-001 201451669-201480846 protein_coding
  ENST00000392249 STRADB-003 201451796-201480846 protein_coding
  ENST00000415688 STRADB-009 201478150-201480523 protein_coding
  ENST00000447698 STRADB-005 201451734-201474707 nonsense_mediated_decay
  ENST00000458269 STRADB-006 201387858-201478113 protein_coding
  ENST00000466770 STRADB-010 201479142-201480348 retained_intron
  ENST00000468123 STRADB-008 201475671-201478567 retained_intron
  ENST00000484098 STRADB-011 201472857-201477725 retained_intron
  ENST00000488196 STRADB-004 201451734-201458823 processed_transcript
  ENST00000498648 STRADB-007 201474622-201478191 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000194530ENST00000392249ENST00000415688ENST00000468123
Transcript ID Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000194530 10.519±0.00 4.509±0.00 15.309±0.00 6.841±1.73 6.037±0.00 6.959±0.00 9.583±3.16 4.917±1.26 7.809±0.61 N/A
ENST00000392249 N/A N/A N/A 3.003±0.00 N/A N/A N/A 4.492±0.00 6.919±0.00 5.902±0.00
ENST00000415688 N/A N/A N/A N/A 8.188±0.00 N/A N/A N/A N/A N/A
ENST00000468123 N/A N/A N/A N/A N/A N/A 12.478±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00089O CIL_00089O_0001 VISTA 2:201132231-201734391
CIL_0000JJ CIL_0000JJ_0002 CGP 2:201377207-201480846
CIL_00020Q CIL_00020Q_0001 CGP 2:201387858-201619178

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000902 IEA cell morphogenesis
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006468 IEA protein phosphorylation
GO:0006611 IDA protein export from nucleus
GO:0007050 TAS cell cycle arrest
GO:0007254 IEA JNK cascade
GO:0008286 TAS insulin receptor signaling pathway
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0032147 IDA activation of protein kinase activity
GO:2001240 IEA negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000088225 STRADB STE20-related kinase adaptor beta protein_coding Danio_rerio
ENSMUSG00000026027 Stradb STE20-related kinase adaptor beta protein_coding Mus_musculus

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