C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: malic enzyme 2, NAD(+)-dependent, mitochondrial
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000082212 ME2 9606 + 18:50879049-50954257 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000321341 ME2-001 50879049-50954257 protein_coding
  ENST00000382927 ME2-002 50879120-50947890 protein_coding
  ENST00000585680 ME2-004 50925860-50947445 processed_transcript
  ENST00000589330 ME2-003 50917242-50920711 retained_intron
  ENST00000591925 ME2-005 50940130-50947154 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000321341ENST00000382927ENST00000585680ENST00000589330ENST00000591925
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000321341 0.530±0.00 1.118±0.00 0.208±0.00 0.746±0.06 0.616±0.03 0.515±0.00 0.611±0.21 0.721±0.49 0.635±0.30 0.206±0.00 0.296±0.00 0.717±0.24 0.421±0.15 0.962±0.14
ENST00000382927 7.763±0.00 6.376±0.00 2.428±0.00 6.195±2.02 5.025±0.82 7.144±1.19 4.215±2.46 8.317±0.00 5.963±2.45 4.296±0.29 3.264±0.71 6.121±2.59 7.047±0.74 8.858±5.32
ENST00000585680 N/A 7.799±0.00 N/A 7.935±0.00 4.753±0.00 6.777±0.00 N/A 3.554±0.00 3.222±0.00 4.501±0.00 3.812±0.37 5.761±0.00 5.713±0.98 17.128±0.00
ENST00000589330 N/A N/A 5.091±0.00 N/A 15.141±0.00 N/A N/A N/A N/A 8.398±0.00 N/A 10.631±0.00 N/A N/A
ENST00000591925 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 14.427±0.00 11.992±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004471 IEA malate dehydrogenase (decarboxylating) (NAD+) activity
GO:0005739 IDA mitochondrion
GO:0006108 IEA malate metabolic process
GO:0008948 IEA oxaloacetate decarboxylase activity
GO:0009055 TAS electron carrier activity
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0046872 IEA metal ion binding
GO:0051287 IEA NAD binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015453 me2 malic enzyme 2, NAD(+)-dependent, mitochondrial protein_coding Danio_rerio
ENSDARG00000086153 me2 malic enzyme 2, NAD(+)-dependent, mitochondrial protein_coding Danio_rerio
ENSMUSG00000024556 Me2 malic enzyme 2, NAD(+)-dependent, mitochondrial protein_coding Mus_musculus

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