C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: discs, large homolog 3 (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000082458 DLG3 9606 + X:70444861-70505490 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000194900 DLG3-003 70444861-70505490 protein_coding
  ENST00000374355 DLG3-002 70452305-70505487 protein_coding
  ENST00000374360 DLG3-001 70444969-70505487 protein_coding
  ENST00000461646 DLG3-008 70497165-70502371 processed_transcript
  ENST00000463252 DLG3-005 70445136-70503946 retained_intron
  ENST00000466140 DLG3-007 70479118-70499903 processed_transcript
  ENST00000489733 DLG3-004 70455103-70498558 processed_transcript
  ENST00000494493 DLG3-006 70455107-70492237 processed_transcript
  ENST00000496931 DLG3-009 70499965-70500989 retained_intron
  ENST00000542398 DLG3-201 70455096-70505485 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000374355ENST00000374360ENST00000461646ENST00000463252ENST00000466140ENST00000489733ENST00000542398
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000374355 0.885±0.00 0.897±0.00 2.184±0.00 N/A 1.586±0.82 1.623±0.00 0.233±0.03 0.646±0.55 3.015±0.00 2.497±0.00 0.236±0.00 4.601±2.31 1.329±0.52 0.771±0.23
ENST00000374360 N/A N/A N/A 5.648±0.32 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.276±0.00
ENST00000461646 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 19.107±0.00 5.870±0.00 2.696±0.15
ENST00000463252 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.925±0.00 N/A N/A
ENST00000466140 N/A N/A 2.766±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000489733 N/A N/A N/A N/A N/A N/A N/A 0.831±0.00 N/A N/A 0.469±0.00 4.254±0.00 N/A N/A
ENST00000542398 0.977±0.00 N/A N/A N/A 1.683±0.00 3.408±0.00 0.913±0.00 6.397±0.00 0.216±0.00 0.724±0.38 N/A 2.512±0.27 2.156±0.72 2.341±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00009K CIL_00009K_0001 CGP X:70423031-70505490
CIL_0000YJ CIL_0000YJ_0002 CGP X:70444861-70908731

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001736 IEA establishment of planar polarity
GO:0005515 IEA protein binding
GO:0005615 IDA extracellular space
GO:0005737 IEA cytoplasm
GO:0005886 TAS plasma membrane
GO:0005911 IEA cell-cell junction
GO:0005923 IEA tight junction
GO:0007268 TAS synaptic transmission
GO:0007411 TAS axon guidance
GO:0008022 IEA protein C-terminus binding
GO:0008285 NAS negative regulation of cell proliferation
GO:0010923 IDA negative regulation of phosphatase activity
GO:0019902 IDA phosphatase binding
GO:0019903 IEA protein phosphatase binding
GO:0019904 IEA protein domain specific binding
GO:0030165 IEA PDZ domain binding
GO:0030426 IEA growth cone
GO:0031625 IEA ubiquitin protein ligase binding
GO:0032281 IEA alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
GO:0035255 IEA ionotropic glutamate receptor binding
GO:0043025 IEA neuronal cell body
GO:0043198 IEA dendritic shaft
GO:0045197 IEA establishment or maintenance of epithelial cell apical/basal polarity
GO:0045202 IEA synapse

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012203 dlg3 discs, large homolog 3 (Drosophila) protein_coding Danio_rerio
ENSDARG00000076796 dlg3 discs, large homolog 3 (Drosophila) protein_coding Danio_rerio
ENSMUSG00000000881 Dlg3 discs, large homolog 3 (Drosophila) protein_coding Mus_musculus

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