C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: peptidylprolyl isomerase E (cyclophilin E)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000084072 PPIE 9606 + 1:39692182-39763914 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000324379 PPIE-001 39738882-39753707 protein_coding
  ENST00000356511 PPIE-002 39738885-39763914 protein_coding
  ENST00000372830 PPIE-003 39738901-39763914 protein_coding
  ENST00000372835 PPIE-007 39738901-39753444 protein_coding
  ENST00000456578 PPIE-015 39738886-39741843 retained_intron
  ENST00000467741 PPIE-014 39761199-39763914 processed_transcript
  ENST00000470018 PPIE-008 39692182-39745403 protein_coding
  ENST00000470213 PPIE-009 39738901-39753266 protein_coding
  ENST00000474804 PPIE-011 39738904-39749088 nonsense_mediated_decay
  ENST00000475350 PPIE-013 39738908-39753716 nonsense_mediated_decay
  ENST00000480169 PPIE-010 39738990-39745498 processed_transcript
  ENST00000482751 PPIE-005 39738890-39753716 retained_intron
  ENST00000485507 PPIE-012 39738879-39742481 retained_intron
  ENST00000495526 PPIE-004 39738888-39753716 nonsense_mediated_decay
  ENST00000497370 PPIE-006 39738901-39753052 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000324379ENST00000356511ENST00000372830ENST00000372835ENST00000470213ENST00000474804ENST00000475350ENST00000482751ENST00000495526ENST00000497370
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000324379 14.773±0.00 10.017±0.00 N/A 4.721±2.00 9.273±0.00 10.679±8.45 4.959±3.80 7.071±5.61 3.127±1.98 9.450±0.00 8.030±5.01 17.356±10.65 18.545±2.67 22.444±4.99
ENST00000356511 N/A N/A N/A 4.386±3.49 4.139±0.00 9.166±0.00 N/A 4.009±0.00 N/A N/A 0.952±0.00 5.697±1.88 N/A N/A
ENST00000372830 N/A N/A N/A 0.809±0.00 2.940±0.00 N/A N/A 0.694±0.00 N/A 1.486±0.00 N/A N/A N/A N/A
ENST00000372835 N/A N/A N/A N/A N/A N/A N/A N/A 3.150±0.00 N/A N/A N/A N/A N/A
ENST00000470213 N/A N/A N/A 1.250±0.00 N/A N/A 0.403±0.00 N/A 1.180±0.00 N/A N/A 6.090±0.00 N/A 14.377±0.00
ENST00000474804 N/A N/A N/A N/A N/A N/A N/A N/A 2.006±0.00 N/A N/A N/A N/A N/A
ENST00000475350 N/A 8.779±0.00 N/A N/A N/A N/A 1.910±1.44 N/A 3.848±0.00 2.733±0.40 1.068±0.00 5.603±0.00 8.095±0.00 12.735±0.00
ENST00000482751 N/A N/A 0.959±0.00 N/A N/A N/A N/A N/A N/A 0.589±0.00 N/A N/A N/A N/A
ENST00000495526 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.286±0.00 N/A 0.907±0.00 N/A N/A
ENST00000497370 N/A N/A 2.218±0.00 N/A N/A N/A 0.509±0.00 N/A N/A 1.635±0.00 N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0000398 IC mRNA splicing, via spliceosome
GO:0000413 IEA protein peptidyl-prolyl isomerization
GO:0003676 IEA nucleic acid binding
GO:0003723 TAS:IEA RNA binding
GO:0003755 IEA:TAS peptidyl-prolyl cis-trans isomerase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006355 IMP regulation of transcription, DNA-templated
GO:0006457 IEA protein folding
GO:0016018 TAS cyclosporin A binding
GO:0044822 IDA poly(A) RNA binding
GO:0045070 IMP positive regulation of viral genome replication
GO:0071013 IDA catalytic step 2 spliceosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059270 ppie peptidylprolyl isomerase E (cyclophilin E) protein_coding Danio_rerio
ENSMUSG00000028651 Ppie peptidylprolyl isomerase E (cyclophilin E) protein_coding Mus_musculus

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