C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ubiquitin interaction motif containing 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000087206 UIMC1 9606 - 5:176905005-177022633 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000377227 UIMC1-001 176905005-177006408 protein_coding
  ENST00000417486 UIMC1-002 176969941-177006365 retained_intron
  ENST00000428382 UIMC1-008 176982521-177006570 protein_coding
  ENST00000503273 UIMC1-010 176908633-176968889 processed_transcript
  ENST00000505229 UIMC1-011 176905658-176907307 retained_intron
  ENST00000505879 UIMC1-009 176975416-176980276 processed_transcript
  ENST00000506128 UIMC1-006 176905050-177006581 protein_coding
  ENST00000507513 UIMC1-007 176970832-177006714 protein_coding
  ENST00000509236 UIMC1-014 176969283-177022602 protein_coding
  ENST00000510376 UIMC1-012 176905193-176906176 retained_intron
  ENST00000510698 UIMC1-201 176905066-176970793 protein_coding
  ENST00000511320 UIMC1-004 176905050-177006751 protein_coding
  ENST00000512031 UIMC1-003 176905053-177006715 nonsense_mediated_decay
  ENST00000515488 UIMC1-013 176970690-177022633 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000377227ENST00000417486ENST00000503273ENST00000506128ENST00000507513ENST00000509236ENST00000510376ENST00000510698ENST00000511320ENST00000512031ENST00000515488
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000377227 N/A N/A 0.609±0.00 N/A N/A N/A N/A N/A N/A N/A 0.353±0.00 3.694±0.00 N/A N/A
ENST00000417486 N/A N/A 0.952±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000503273 N/A N/A N/A 6.103±0.00 N/A 3.194±0.00 N/A N/A 4.104±0.00 3.124±0.00 N/A N/A N/A N/A
ENST00000506128 N/A N/A N/A 1.670±0.00 N/A N/A 1.707±0.75 N/A N/A N/A 1.284±0.00 N/A N/A 22.350±0.00
ENST00000507513 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.617±0.00 N/A N/A N/A
ENST00000509236 N/A N/A N/A 4.268±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000510376 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 10.788±0.00 N/A N/A
ENST00000510698 N/A 9.573±0.00 N/A 3.807±0.00 3.282±0.15 8.093±0.00 2.283±0.00 3.307±2.49 1.990±0.01 5.148±0.00 1.547±0.73 5.711±0.43 2.303±0.95 19.959±6.88
ENST00000511320 2.079±0.00 5.605±0.00 0.580±0.00 1.079±0.00 1.669±0.55 4.179±0.00 N/A 3.636±0.00 1.627±0.00 4.671±0.00 4.168±0.00 3.186±1.75 2.288±0.96 26.771±3.96
ENST00000512031 N/A N/A N/A N/A N/A N/A 2.965±0.00 1.367±0.00 N/A 2.066±0.53 N/A N/A N/A N/A
ENST00000515488 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.129±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00098R CIL_00098R_0001 VISTA 5:176349731-176951529
CIL_0001A8 CIL_0001A8_0001 CGP 5:176880869-177022633
CIL_0000OX CIL_0000OX_0003 CGP 5:176905005-177081189

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006302 IMP double-strand break repair
GO:0006351 IEA transcription, DNA-templated
GO:0010212 IMP response to ionizing radiation
GO:0031572 IMP G2 DNA damage checkpoint
GO:0042393 IDA histone binding
GO:0045739 IMP positive regulation of DNA repair
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0046965 IEA retinoid X receptor binding
GO:0070530 IDA K63-linked polyubiquitin binding
GO:0070531 IDA BRCA1-A complex
GO:0070537 IMP histone H2A K63-linked deubiquitination

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000089679 UIMC1 (1 of 2) ubiquitin interaction motif containing 1 protein_coding Danio_rerio
ENSDARG00000091187 UIMC1 (2 of 2) ubiquitin interaction motif containing 1 protein_coding Danio_rerio
ENSMUSG00000025878 Uimc1 ubiquitin interaction motif containing 1 protein_coding Mus_musculus

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