C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sialic acid binding Ig-like lectin 1, sialoadhesin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000088827 SIGLEC1 9606 - 20:3686970-3707128 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000344754 SIGLEC1-001 3686970-3707128 protein_coding
  ENST00000419548 SIGLEC1-002 3686970-3693079 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000344754ENST00000419548
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000344754 0.994±0.00 2.407±0.00 0.128±0.00 0.182±0.00 1.726±0.00 0.172±0.00 1.170±0.88 0.413±0.17 1.066±0.60 1.675±0.75 1.016±0.00 0.644±0.45 7.596±0.29 0.616±0.17
ENST00000419548 N/A N/A N/A 0.080±0.06 1.093±0.00 0.830±0.00 0.637±0.53 0.530±0.00 0.872±0.49 0.465±0.00 0.971±0.00 0.592±0.40 3.623±1.65 1.121±0.48

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003D8 CIL_0003D8_0001 CGP 20:3667965-3707128
CIL_0004Q3 CIL_0004Q3_0001 CGP 20:3686970-3753111

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005576 IEA extracellular region
GO:0005886 IEA plasma membrane
GO:0006897 IEA endocytosis
GO:0006954 NAS inflammatory response
GO:0007160 NAS cell-matrix adhesion
GO:0016021 NAS integral component of membrane
GO:0016337 NAS single organismal cell-cell adhesion
GO:0030246 NAS carbohydrate binding
GO:0070234 IEA positive regulation of T cell apoptotic process
GO:2001238 IEA positive regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000027322 Siglec1 sialic acid binding Ig-like lectin 1, sialoadhesin protein_coding Mus_musculus

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