C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tescalcin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000088992 TESC 9606 - 12:117038923-117099479 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000335209 TESC-001 117038924-117099469 protein_coding
  ENST00000462502 TESC-003 117046480-117099408 nonsense_mediated_decay
  ENST00000470612 TESC-002 117038923-117099479 nonsense_mediated_decay
  ENST00000482176 TESC-005 117048798-117099431 retained_intron
  ENST00000535198 TESC-004 117046569-117053995 processed_transcript
  ENST00000541210 TESC-201 117038925-117099446 protein_coding
  ENST00000549210 TESC-007 117038957-117046831 protein_coding
  ENST00000552139 TESC-006 117075297-117098655 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000335209ENST00000470612ENST00000482176ENST00000535198ENST00000541210ENST00000549210
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000335209 3.995±0.00 9.141±0.00 0.584±0.00 6.948±0.84 6.515±0.00 2.381±1.59 12.397±9.26 10.508±0.00 2.755±1.89 8.263±7.76 0.167±0.00 9.903±4.33 12.919±5.31 17.371±1.53
ENST00000470612 N/A N/A N/A 6.084±0.00 0.782±0.00 0.744±0.61 0.834±0.00 N/A N/A N/A N/A 7.202±8.93 4.071±0.21 6.031±1.31
ENST00000482176 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.323±0.00 0.930±0.00 N/A N/A
ENST00000535198 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.513±0.00 0.485±0.00 15.639±10.05 9.138±0.00 14.149±0.00
ENST00000541210 4.665±0.00 N/A N/A 4.822±0.00 N/A 3.089±0.00 1.578±0.00 0.521±0.00 N/A 0.719±0.00 0.216±0.00 0.903±0.00 N/A 13.912±0.00
ENST00000549210 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.374±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 ISS magnesium ion binding
GO:0001726 ISS ruffle
GO:0004860 IEA protein kinase inhibitor activity
GO:0005509 IDA:IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0006469 IEA negative regulation of protein kinase activity
GO:0008285 IMP negative regulation of cell proliferation
GO:0008584 IEA male gonad development
GO:0010628 IMP positive regulation of gene expression
GO:0019212 ISS phosphatase inhibitor activity
GO:0030027 IDA lamellipodium
GO:0030154 IEA cell differentiation
GO:0030219 IEA megakaryocyte differentiation
GO:0030854 IDA positive regulation of granulocyte differentiation
GO:0032417 IDA positive regulation of sodium:proton antiporter activity
GO:0033628 IMP regulation of cell adhesion mediated by integrin
GO:0042803 ISS protein homodimerization activity
GO:0043086 ISS negative regulation of catalytic activity
GO:0045654 IMP positive regulation of megakaryocyte differentiation
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0050821 IDA protein stabilization
GO:0051604 IDA protein maturation
GO:0071300 IDA cellular response to retinoic acid
GO:0072661 IDA protein targeting to plasma membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000028346 tesca tescalcin a protein_coding Danio_rerio
ENSDARG00000030839 tescb tescalcin b protein_coding Danio_rerio
ENSMUSG00000029359 Tesc tescalcin protein_coding Mus_musculus

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