C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: pleckstrin homology domain containing, family G (with RhoGef domain) member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000090924 PLEKHG2 9606 + 19:39412585-39428415 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000205135 PLEKHG2-003 39415193-39425739 protein_coding
  ENST00000409797 PLEKHG2-002 39413665-39425516 protein_coding
  ENST00000425673 PLEKHG2-001 39412585-39428415 protein_coding
  ENST00000438123 PLEKHG2-004 39413528-39415260 protein_coding
  ENST00000451354 PLEKHG2-006 39413812-39416597 protein_coding
  ENST00000458508 PLEKHG2-008 39413309-39425437 protein_coding
  ENST00000474449 PLEKHG2-007 39421666-39422828 retained_intron
  ENST00000478523 PLEKHG2-005 39417845-39421113 retained_intron
  ENST00000594124 PLEKHG2-016 39424771-39425665 protein_coding
  ENST00000594161 PLEKHG2-014 39424388-39425516 protein_coding
  ENST00000594307 PLEKHG2-011 39421035-39422216 retained_intron
  ENST00000595920 PLEKHG2-009 39413150-39414232 protein_coding
  ENST00000596339 PLEKHG2-015 39424563-39425495 protein_coding
  ENST00000596443 PLEKHG2-010 39420801-39425473 protein_coding
  ENST00000598238 PLEKHG2-013 39424311-39425514 protein_coding
  ENST00000600210 PLEKHG2-012 39423428-39425512 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000205135ENST00000409797ENST00000425673ENST00000451354ENST00000458508ENST00000474449ENST00000478523ENST00000594307ENST00000596339
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000205135 N/A 4.504±0.00 0.395±0.00 N/A 1.200±0.98 0.996±0.00 1.563±0.00 1.446±0.00 0.404±0.03 8.107±0.00 0.277±0.00 3.116±0.96 4.421±0.17 1.057±0.24
ENST00000409797 N/A N/A N/A 0.109±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 3.297±0.00 3.151±0.00
ENST00000425673 2.506±0.00 2.419±0.00 N/A 0.384±0.00 1.667±0.00 0.452±0.27 0.614±0.53 0.553±0.00 0.260±0.00 3.928±0.00 0.298±0.00 2.818±1.29 1.656±0.60 1.320±0.40
ENST00000451354 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.153±0.00 13.252±0.00 N/A 6.685±0.00
ENST00000458508 2.961±0.00 2.693±0.00 N/A 0.477±0.42 2.316±0.00 0.704±0.47 N/A 0.720±0.54 N/A 7.204±0.00 0.773±0.59 3.355±0.00 1.594±0.22 2.643±0.55
ENST00000474449 N/A N/A N/A N/A N/A N/A 0.384±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000478523 N/A N/A N/A 0.162±0.00 N/A 0.786±0.00 N/A 0.249±0.00 N/A N/A N/A N/A N/A N/A
ENST00000594307 N/A N/A N/A N/A N/A N/A 3.504±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000596339 N/A N/A N/A 0.341±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005829 TAS cytosol
GO:0007264 TAS small GTPase mediated signal transduction
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0043065 TAS positive regulation of apoptotic process
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0097190 TAS apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058459 plekhg2 pleckstrin homology domain containing, family G (with RhoGef domain) member 2 protein_coding Danio_rerio
ENSMUSG00000037552 Plekhg2 pleckstrin homology domain containing, family G (with RhoGef domain) member 2 protein_coding Mus_musculus

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