C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: oxysterol binding protein-like 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000091039 OSBPL8 9606 - 12:76351797-76559809 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261183 OSBPL8-001 76351800-76559809 protein_coding
  ENST00000393249 OSBPL8-002 76351797-76559535 protein_coding
  ENST00000393250 OSBPL8-004 76355836-76559809 protein_coding
  ENST00000546946 OSBPL8-006 76369718-76423266 protein_coding
  ENST00000547540 OSBPL8-003 76369713-76559748 protein_coding
  ENST00000547544 OSBPL8-011 76450901-76559504 protein_coding
  ENST00000548341 OSBPL8-014 76397856-76486108 protein_coding
  ENST00000548485 OSBPL8-017 76369219-76371862 retained_intron
  ENST00000548535 OSBPL8-016 76386030-76389984 retained_intron
  ENST00000549570 OSBPL8-009 76402699-76559712 protein_coding
  ENST00000549646 OSBPL8-013 76402756-76559793 protein_coding
  ENST00000550628 OSBPL8-008 76402724-76559805 protein_coding
  ENST00000550865 OSBPL8-015 76390281-76394737 retained_intron
  ENST00000551927 OSBPL8-010 76450893-76559569 protein_coding
  ENST00000552178 OSBPL8-012 76487550-76559528 processed_transcript
  ENST00000552586 OSBPL8-018 76371212-76373489 retained_intron
  ENST00000553139 OSBPL8-007 76399881-76559808 protein_coding
  ENST00000611266 OSBPL8-201 76351800-76559809 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000261183ENST00000393249ENST00000393250ENST00000547540ENST00000548485ENST00000550865ENST00000552586
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000261183 1.472±0.00 N/A 2.554±0.00 4.910±0.00 5.036±0.00 2.045±0.00 4.053±0.00 1.222±0.97 4.595±0.00 4.013±0.00 0.685±0.00 1.593±0.00 4.044±2.09
ENST00000393249 N/A N/A N/A N/A N/A N/A N/A 0.727±0.00 N/A N/A 0.871±0.00 N/A 0.860±0.00
ENST00000393250 N/A 8.191±0.00 4.263±1.21 8.794±0.00 4.289±0.00 1.964±0.00 3.530±0.00 6.854±0.00 10.759±0.00 0.675±0.00 4.992±1.19 N/A 1.794±0.00
ENST00000547540 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.629±0.00 1.774±0.00 2.231±0.00
ENST00000548485 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.049±0.00 11.548±0.00
ENST00000550865 N/A N/A N/A N/A N/A N/A 11.052±0.00 N/A N/A N/A N/A N/A N/A
ENST00000552586 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.678±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002B9 CIL_0002B9_0002 CGP 12:76351797-76853696

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0006869 IEA lipid transport
GO:0010891 IDA negative regulation of sequestering of triglyceride
GO:0015485 IDA cholesterol binding
GO:0016020 IDA membrane
GO:0030336 IEA negative regulation of cell migration
GO:0031965 IEA nuclear membrane
GO:0045444 IDA fat cell differentiation
GO:0046628 IEA positive regulation of insulin receptor signaling pathway
GO:0051897 IEA positive regulation of protein kinase B signaling
GO:0090204 IEA protein localization to nuclear pore

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039724 CABZ01007893.1 Oxysterol-binding protein protein_coding Danio_rerio
ENSMUSG00000020189 Osbpl8 oxysterol binding protein-like 8 protein_coding Mus_musculus

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