C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: apolipoprotein H (beta-2-glycoprotein I)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000091583 APOH 9606 - 17:66212033-66256525 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000205948 APOH-001 66212033-66229417 protein_coding
  ENST00000577982 APOH-003 66220614-66256525 protein_coding
  ENST00000581797 APOH-002 66216791-66228637 protein_coding
  ENST00000585162 APOH-004 66212039-66220630 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000205948ENST00000577982ENST00000581797ENST00000585162
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000205948 N/A N/A 0.949±0.00 0.565±0.00 5.248±0.00 N/A 0.050±0.03 1221.980±1221.65 1388.692±1388.57 0.343±0.14 0.028±0.00 0.067±0.02 0.080±0.02 0.045±0.01
ENST00000577982 0.044±0.00 0.092±0.00 N/A 0.101±0.00 0.047±0.00 N/A N/A N/A 0.176±0.00 N/A 0.096±0.00 0.251±0.01 N/A 0.127±0.08
ENST00000581797 N/A N/A N/A N/A N/A N/A 0.031±0.00 N/A N/A 0.576±0.00 N/A N/A N/A 0.042±0.00
ENST00000585162 N/A 0.032±0.00 N/A N/A N/A 0.244±0.00 N/A N/A 0.470±0.00 N/A 0.141±0.00 N/A 0.220±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001937 IDA negative regulation of endothelial cell proliferation
GO:0001948 IPI glycoprotein binding
GO:0005515 IPI protein binding
GO:0005543 IDA phospholipid binding
GO:0005615 IDA extracellular space
GO:0006641 IDA triglyceride metabolic process
GO:0007597 IDA blood coagulation, intrinsic pathway
GO:0008201 IEA heparin binding
GO:0008289 IDA lipid binding
GO:0009986 IDA cell surface
GO:0010596 IDA negative regulation of endothelial cell migration
GO:0016525 IDA negative regulation of angiogenesis
GO:0030193 IEA regulation of blood coagulation
GO:0030194 TAS positive regulation of blood coagulation
GO:0030195 IDA negative regulation of blood coagulation
GO:0031012 IDA extracellular matrix
GO:0031639 IDA plasminogen activation
GO:0033033 IDA negative regulation of myeloid cell apoptotic process
GO:0034197 ISS triglyceride transport
GO:0034361 IDA very-low-density lipoprotein particle
GO:0034364 IDA high-density lipoprotein particle
GO:0034392 IDA negative regulation of smooth muscle cell apoptotic process
GO:0042627 IDA chylomicron
GO:0042802 IPI identical protein binding
GO:0051006 IDA positive regulation of lipoprotein lipase activity
GO:0051917 IDA regulation of fibrinolysis
GO:0051918 IDA negative regulation of fibrinolysis
GO:0060230 IDA lipoprotein lipase activator activity
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000000049 Apoh apolipoprotein H protein_coding Mus_musculus

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