C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: chymase 1, mast cell
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000092009 CMA1 9606 - 14:24505353-24508265 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000206446 CMA1-002 24505506-24508265 protein_coding
  ENST00000250378 CMA1-001 24505353-24508265 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000206446ENST00000250378
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000206446 0.546±0.00 1.604±0.00 0.032±0.00 0.358±0.29 0.135±0.00 N/A 0.143±0.00 N/A N/A N/A 0.074±0.00 0.212±0.00 0.615±0.00
ENST00000250378 0.410±0.00 3.938±0.00 0.041±0.00 0.848±0.00 0.289±0.00 0.405±0.18 N/A 1.265±0.00 0.157±0.00 0.161±0.00 N/A 0.733±0.00 0.394±0.13

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004OA CIL_0004OA_0001 CGP 14:24439766-24508265
CIL_000765 CIL_000765_0004 CGP 14:24505353-24576260

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002003 TAS angiotensin maturation
GO:0003824 IEA catalytic activity
GO:0004252 IEA serine-type endopeptidase activity
GO:0005576 TAS extracellular region
GO:0005622 IEA intracellular
GO:0006508 IEA proteolysis
GO:0006518 IEA peptide metabolic process
GO:0008236 TAS serine-type peptidase activity
GO:0022617 TAS extracellular matrix disassembly
GO:0030198 TAS extracellular matrix organization
GO:0030901 IEA midbrain development
GO:0031012 IDA extracellular matrix
GO:0042277 IEA peptide binding
GO:0044267 TAS cellular protein metabolic process
GO:0045766 IEA positive regulation of angiogenesis
GO:0050720 IDA interleukin-1 beta biosynthetic process
GO:0050727 IC regulation of inflammatory response
GO:0071333 IEA cellular response to glucose stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055986 protein_coding Danio_rerio
ENSDARG00000076814 protein_coding Danio_rerio
ENSDARG00000078451 protein_coding Danio_rerio
ENSDARG00000093990 protein_coding Danio_rerio
ENSMUSG00000022225 Cma1 chymase 1, mast cell protein_coding Mus_musculus

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