C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: solute carrier family 7 (amino acid transporter light chain, L system), member 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000092068 SLC7A8 9606 - 14:23125295-23183674 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000316902 SLC7A8-001 23125295-23183640 protein_coding
  ENST00000339733 SLC7A8-006 23125295-23155309 nonsense_mediated_decay
  ENST00000397310 SLC7A8-008 23125297-23130143 retained_intron
  ENST00000422941 SLC7A8-201 23125297-23154450 protein_coding
  ENST00000453702 SLC7A8-002 23126668-23154401 protein_coding
  ENST00000469263 SLC7A8-004 23125302-23183641 protein_coding
  ENST00000524758 SLC7A8-009 23166409-23183674 protein_coding
  ENST00000525062 SLC7A8-010 23166458-23183650 protein_coding
  ENST00000528186 SLC7A8-012 23129598-23138211 retained_intron
  ENST00000528806 SLC7A8-013 23129261-23138019 retained_intron
  ENST00000528860 SLC7A8-007 23126759-23154393 nonsense_mediated_decay
  ENST00000529705 SLC7A8-005 23126751-23155458 protein_coding
  ENST00000532568 SLC7A8-011 23139424-23146932 processed_transcript
  ENST00000617478 SLC7A8-202 23125302-23183660 protein_coding
  ENST00000618208 SLC7A8-203 23127262-23183660 protein_coding
  ENST00000621729 SLC7A8-204 23127026-23166465 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000316902ENST00000339733ENST00000422941ENST00000453702ENST00000469263ENST00000524758ENST00000525062ENST00000528186ENST00000529705ENST00000532568ENST00000617478ENST00000618208
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000316902 3.459±0.00 N/A 7.947±0.00 1.699±0.00 N/A N/A 3.103±0.00 8.788±7.03 1.112±0.00 0.472±0.00 3.000±0.00 10.985±10.83 4.032±0.85 3.318±0.00
ENST00000339733 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.816±1.92 N/A N/A N/A
ENST00000422941 N/A 3.623±0.00 N/A N/A 1.548±0.00 0.441±0.00 N/A 13.903±0.00 2.258±0.00 N/A 8.036±0.00 4.509±4.10 N/A N/A
ENST00000453702 N/A N/A N/A N/A N/A N/A N/A N/A 0.896±0.00 N/A N/A 13.556±0.00 N/A N/A
ENST00000469263 N/A 0.974±0.00 N/A 0.773±0.00 0.844±0.19 2.453±0.00 0.129±0.00 N/A 0.784±0.00 N/A 0.352±0.00 0.665±0.00 N/A 2.438±0.00
ENST00000524758 N/A N/A N/A N/A N/A N/A N/A 3.100±0.00 N/A N/A N/A N/A N/A N/A
ENST00000525062 N/A N/A 11.079±0.00 N/A 1.529±0.00 2.930±0.00 N/A N/A N/A N/A N/A 1.318±0.00 N/A N/A
ENST00000528186 N/A N/A N/A N/A N/A N/A 0.452±0.00 N/A N/A N/A 3.968±0.00 N/A N/A N/A
ENST00000529705 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.081±0.00 N/A N/A
ENST00000532568 N/A N/A N/A N/A N/A N/A N/A N/A 3.354±0.00 N/A N/A N/A N/A N/A
ENST00000617478 N/A N/A 2.850±0.00 7.187±0.00 N/A N/A N/A N/A 1.134±0.00 N/A N/A 4.349±0.00 4.882±2.55 N/A
ENST00000618208 N/A N/A 14.741±0.00 N/A 2.254±0.00 N/A N/A N/A 1.024±0.00 1.406±0.00 0.961±0.00 2.072±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00090C CIL_00090C_0001 VISTA 14:23078458-23681621
CIL_0006MX CIL_0006MX_0001 CGP 14:23117304-23183674

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003333 IEA amino acid transmembrane transport
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005886 IDA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006520 TAS cellular amino acid metabolic process
GO:0006810 TAS:IEA transport
GO:0006811 TAS ion transport
GO:0006865 IDA:IEA amino acid transport
GO:0007596 TAS blood coagulation
GO:0009636 NAS response to toxic substance
GO:0015101 IDA organic cation transmembrane transporter activity
GO:0015171 ISS:IEA amino acid transmembrane transporter activity
GO:0015175 TAS neutral amino acid transmembrane transporter activity
GO:0015179 IEA L-amino acid transmembrane transporter activity
GO:0015695 IDA organic cation transport
GO:0015804 ISS neutral amino acid transport
GO:0015807 IEA L-amino acid transport
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019534 IDA toxin transporter activity
GO:0042605 ISS peptide antigen binding
GO:0050900 TAS leukocyte migration
GO:0055065 NAS metal ion homeostasis
GO:0055085 TAS:IEA transmembrane transport
GO:0070062 IDA extracellular vesicular exosome
GO:1901998 IDA toxin transport
GO:1902475 IEA L-alpha-amino acid transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000054343 SLC7A8 (1 of 2) solute carrier family 7 (amino acid transporter light chain, L system), member 8 protein_coding Danio_rerio
ENSDARG00000075831 SLC7A8B solute carrier family 7 (cationic amino acid transporter, y+ system), member 8a (slc7a8a), mRNA protein_coding Danio_rerio
ENSMUSG00000022180 Slc7a8 solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 protein_coding Mus_musculus

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