C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ezrin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000092820 EZR 9606 - 6:158765741-158819412 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000337147 EZR-002 158765741-158818227 protein_coding
  ENST00000367075 EZR-001 158765748-158819412 protein_coding
  ENST00000392177 EZR-201 158765742-158789474 protein_coding
  ENST00000476189 EZR-003 158783534-158819349 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000337147ENST00000367075ENST00000392177
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000337147 2.814±0.00 24.123±0.00 3.615±0.00 19.760±18.78 2.988±0.33 7.402±0.00 15.861±14.64 60.803±0.00 3.588±1.69 78.384±0.00 6.784±0.00 23.444±0.00 22.252±5.12 34.378±0.00
ENST00000367075 18.587±0.00 41.179±0.00 1.895±0.00 6.584±5.03 8.343±7.37 12.602±4.52 15.071±13.99 33.817±0.00 4.569±1.97 48.788±42.07 17.211±0.00 30.147±12.25 64.019±30.50 21.598±14.60
ENST00000392177 N/A N/A 6.714±0.00 5.829±0.00 N/A 15.466±0.00 4.816±0.00 17.667±13.84 5.364±2.72 12.748±0.00 2.570±1.88 67.019±54.32 101.201±9.40 20.802±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004W5 CIL_0004W5_0001 CGP 6:158650014-158819412

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001726 IDA ruffle
GO:0001931 IEA uropod
GO:0003779 IEA actin binding
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0005622 IEA intracellular
GO:0005730 IDA nucleolus
GO:0005737 IEA cytoplasm
GO:0005829 IDA cytosol
GO:0005856 IEA cytoskeleton
GO:0005884 IDA actin filament
GO:0005886 IDA plasma membrane
GO:0005902 IDA microvillus
GO:0005925 IDA focal adhesion
GO:0007016 NAS cytoskeletal anchoring at plasma membrane
GO:0007159 IEP leukocyte cell-cell adhesion
GO:0007411 TAS axon guidance
GO:0008092 IEA cytoskeletal protein binding
GO:0008360 IEA regulation of cell shape
GO:0010628 IGI positive regulation of gene expression
GO:0015629 IDA actin cytoskeleton
GO:0016020 IDA membrane
GO:0016323 ISS basolateral plasma membrane
GO:0016324 IEA apical plasma membrane
GO:0019898 IDA:IEA extrinsic component of membrane
GO:0019904 IEA protein domain specific binding
GO:0022614 IEP membrane to membrane docking
GO:0030175 IDA filopodium
GO:0030315 IEA T-tubule
GO:0030855 IEA epithelial cell differentiation
GO:0030863 TAS cortical cytoskeleton
GO:0031528 IEA microvillus membrane
GO:0031623 IEA receptor internalization
GO:0031982 IDA vesicle
GO:0032403 IEA protein complex binding
GO:0035088 IEA establishment or maintenance of apical/basal cell polarity
GO:0036064 IEA ciliary basal body
GO:0044297 IEA cell body
GO:0044393 IEA microspike
GO:0044822 IDA poly(A) RNA binding
GO:0045121 IEA membrane raft
GO:0045177 IDA apical part of cell
GO:0046847 IEA filopodium assembly
GO:0050839 IPI cell adhesion molecule binding
GO:0051015 IDA actin filament binding
GO:0051017 IDA actin filament bundle assembly
GO:0051286 IEA cell tip
GO:0061028 IGI establishment of endothelial barrier
GO:0070062 IDA extracellular vesicular exosome
GO:0097449 IEA astrocyte projection
GO:0097454 IEA Schwann cell microvillus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000052397 Ezr ezrin protein_coding Mus_musculus

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