C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interleukin 12 receptor, beta 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000096996 IL12RB1 9606 - 19:18058995-18098944 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000322153 IL12RB1-003 18070562-18086932 protein_coding
  ENST00000430026 IL12RB1-008 18080898-18086996 protein_coding
  ENST00000593993 IL12RB1-001 18058995-18087003 protein_coding
  ENST00000594176 IL12RB1-005 18082234-18098927 protein_coding
  ENST00000597416 IL12RB1-007 18083112-18086930 retained_intron
  ENST00000598019 IL12RB1-006 18082187-18098816 protein_coding
  ENST00000600835 IL12RB1-002 18058995-18098944 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000322153ENST00000593993ENST00000600835
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000322153 0.707±0.00 4.828±0.00 0.381±0.35 0.867±0.12 0.364±0.00 0.572±0.00 0.555±0.22 0.337±0.25 2.024±0.00 0.409±0.00 0.433±0.20 1.128±0.28 0.200±0.02
ENST00000593993 0.175±0.00 N/A N/A 0.225±0.00 0.282±0.00 0.131±0.00 N/A 0.084±0.00 N/A N/A 0.273±0.17 0.473±0.06 0.124±0.00
ENST00000600835 N/A N/A 0.221±0.00 N/A N/A N/A N/A N/A 0.769±0.00 N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001916 ISS positive regulation of T cell mediated cytotoxicity
GO:0002230 ISS positive regulation of defense response to virus by host
GO:0002827 ISS positive regulation of T-helper 1 type immune response
GO:0004896 TAS cytokine receptor activity
GO:0005143 IPI interleukin-12 receptor binding
GO:0005515 IEA protein binding
GO:0007165 IC signal transduction
GO:0009897 IEA external side of plasma membrane
GO:0016517 IDA interleukin-12 receptor activity
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0019955 IEA cytokine binding
GO:0032729 IDA positive regulation of interferon-gamma production
GO:0035722 IDA interleukin-12-mediated signaling pathway
GO:0038155 IDA interleukin-23-mediated signaling pathway
GO:0042019 IPI interleukin-23 binding
GO:0042020 IDA interleukin-23 receptor activity
GO:0042022 IDA interleukin-12 receptor complex
GO:0042104 IDA positive regulation of activated T cell proliferation
GO:0043382 ISS positive regulation of memory T cell differentiation
GO:0071346 IDA cellular response to interferon-gamma
GO:0072536 IDA interleukin-23 receptor complex
GO:2000318 ISS positive regulation of T-helper 17 type immune response
GO:2000330 ISS positive regulation of T-helper 17 cell lineage commitment

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000000791 Il12rb1 interleukin 12 receptor, beta 1 protein_coding Mus_musculus

Loading