C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mucosal vascular addressin cell adhesion molecule 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000099866 MADCAM1 9606 + 19:489176-505343 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000215637 MADCAM1-002 496494-505343 protein_coding
  ENST00000346144 MADCAM1-001 496454-505340 protein_coding
  ENST00000382683 MADCAM1-003 496500-504965 protein_coding
  ENST00000587541 MADCAM1-004 489176-505343 protein_coding
  ENST00000613880 MADCAM1-201 496454-505207 protein_coding
  ENST00000617201 MADCAM1-202 496454-505207 protein_coding
  ENST00000619333 MADCAM1-203 496454-505207 protein_coding
  ENST00000621286 MADCAM1-204 496500-504965 protein_coding
  ENST00000622449 MADCAM1-005 497818-498727 retained_intron
  ENST00000622462 MADCAM1-205 496454-505207 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000215637ENST00000346144ENST00000587541ENST00000613880ENST00000621286ENST00000622449ENST00000622462
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000215637 N/A N/A N/A N/A 0.897±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000346144 N/A 0.303±0.00 N/A N/A N/A N/A 0.105±0.00 0.219±0.00 0.528±0.00 0.081±0.00 0.072±0.00 N/A
ENST00000587541 0.166±0.00 0.056±0.00 0.956±0.36 0.402±0.00 0.282±0.00 N/A N/A N/A N/A 0.198±0.00 0.137±0.04 0.566±0.01
ENST00000613880 0.045±0.00 N/A N/A 0.064±0.00 N/A 0.029±0.00 N/A N/A N/A N/A N/A N/A
ENST00000621286 N/A N/A N/A N/A 0.511±0.00 N/A N/A N/A N/A N/A N/A 0.222±0.00
ENST00000622449 N/A N/A 1.085±0.00 N/A N/A 0.086±0.00 N/A N/A N/A N/A N/A N/A
ENST00000622462 N/A N/A N/A N/A 0.058±0.00 N/A N/A N/A N/A 0.046±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007EJ CIL_0007EJ_0001 CGP 19:463346-505343
CIL_0008XG CIL_0008XG_0001 VISTA 19:477571-1083531
CIL_00043J CIL_00043J_0001 CGP 19:489176-519654

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002687 IEA positive regulation of leukocyte migration
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0006955 TAS immune response
GO:0007155 TAS:IEA cell adhesion
GO:0007160 IDA cell-matrix adhesion
GO:0007165 TAS signal transduction
GO:0007229 IDA integrin-mediated signaling pathway
GO:0007568 IEA aging
GO:0016020 TAS:IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030198 TAS extracellular matrix organization
GO:0030216 IEA keratinocyte differentiation
GO:0034113 IMP heterotypic cell-cell adhesion
GO:0043113 IDA receptor clustering
GO:0050776 TAS regulation of immune response
GO:0050900 IEA leukocyte migration
GO:0050901 IDA leukocyte tethering or rolling
GO:0098640 IDA integrin binding involved in cell-matrix adhesion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000020310 Madcam1 mucosal vascular addressin cell adhesion molecule 1 protein_coding Mus_musculus

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