C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: v-crk avian sarcoma virus CT10 oncogene homolog-like
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000099942 CRKL 9606 + 22:20917426-20953749 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000354336 CRKL-001 20917426-20953749 protein_coding
  ENST00000411769 CRKL-002 20917434-20953747 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000354336
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000354336 15.898±0.00 12.522±0.00 2.395±0.00 14.685±5.77 8.216±3.03 9.376±3.81 8.356±5.19 8.204±2.65 7.303±0.07 9.029±3.76 17.783±11.12 15.263±5.61 13.969±0.43 10.664±2.45

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002X5 CIL_0002X5_0001 CGP 22:20858983-20953749
CIL_0002X4 CIL_0002X4_0001 CGP 22:20917426-20981360

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000186 TAS activation of MAPKK activity
GO:0001568 IEA blood vessel development
GO:0004871 TAS signal transducer activity
GO:0005070 TAS SH3/SH2 adaptor activity
GO:0005515 IPI:IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005768 TAS endosome
GO:0005829 TAS cytosol
GO:0007254 TAS JNK cascade
GO:0007265 TAS Ras protein signal transduction
GO:0007389 IEA pattern specification process
GO:0007507 IEA heart development
GO:0009887 IEA organ morphogenesis
GO:0009952 IEA anterior/posterior pattern specification
GO:0009967 TAS positive regulation of signal transduction
GO:0035556 TAS intracellular signal transduction
GO:0044822 IDA poly(A) RNA binding
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048538 IEA thymus development
GO:0060017 IEA parathyroid gland development
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000028699 crkl v-crk sarcoma virus CT10 oncogene homolog (avian)-like protein_coding Danio_rerio
ENSMUSG00000006134 Crkl v-crk sarcoma virus CT10 oncogene homolog (avian)-like protein_coding Mus_musculus

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