C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: peptidylprolyl isomerase (cyclophilin)-like 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100023 PPIL2 9606 + 22:21652270-21700015 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000335025 PPIL2-001 21666009-21700015 protein_coding
  ENST00000398831 PPIL2-006 21666022-21696423 protein_coding
  ENST00000406385 PPIL2-005 21666040-21698276 protein_coding
  ENST00000417788 PPIL2-003 21666023-21697912 nonsense_mediated_decay
  ENST00000446951 PPIL2-004 21685673-21697901 processed_transcript
  ENST00000458567 PPIL2-009 21666023-21681390 protein_coding
  ENST00000462188 PPIL2-007 21694661-21697902 retained_intron
  ENST00000484439 PPIL2-010 21666029-21684878 processed_transcript
  ENST00000485930 PPIL2-012 21672330-21673609 processed_transcript
  ENST00000496819 PPIL2-008 21666009-21670283 retained_intron
  ENST00000498109 PPIL2-011 21666079-21671025 retained_intron
  ENST00000498589 PPIL2-002 21652270-21670237 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000398831ENST00000406385ENST00000417788ENST00000446951ENST00000458567ENST00000498109
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000398831 1.087±0.00 4.211±0.00 2.823±0.00 2.792±0.00 2.538±0.71 1.747±0.00 1.736±0.82 2.305±0.52 1.564±0.00 2.060±0.00 N/A 4.562±1.15 2.538±0.12 N/A
ENST00000406385 N/A N/A N/A N/A 0.727±0.00 N/A 0.380±0.00 N/A N/A 1.799±0.00 N/A N/A 1.371±0.06 N/A
ENST00000417788 1.581±0.00 4.183±0.00 0.492±0.00 2.021±1.15 2.068±0.00 1.002±0.46 1.998±0.00 5.003±0.00 2.626±0.00 1.652±0.00 3.717±0.00 5.856±1.43 3.438±1.03 5.385±1.76
ENST00000446951 2.128±0.00 6.729±0.00 0.672±0.00 N/A 4.604±0.00 1.603±0.72 N/A 2.790±0.41 1.507±0.68 4.091±0.00 3.153±0.00 10.550±1.73 4.311±0.46 7.652±0.00
ENST00000458567 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 9.251±0.00 N/A
ENST00000498109 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.340±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008PT CIL_0008PT_0001 VISTA 22:21299079-21900013
CIL_0003KP CIL_0003KP_0002 CGP 22:21652270-21735834

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000209 IDA protein polyubiquitination
GO:0000413 IEA protein peptidyl-prolyl isomerization
GO:0003755 IEA peptidyl-prolyl cis-trans isomerase activity
GO:0004842 IDA:IEA ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005796 TAS Golgi lumen
GO:0005886 IDA plasma membrane
GO:0006457 IEA protein folding
GO:0007596 TAS blood coagulation
GO:0016567 IEA protein ubiquitination
GO:0034450 IDA ubiquitin-ubiquitin ligase activity
GO:0050900 TAS leukocyte migration
GO:0072659 IMP protein localization to plasma membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002016 ppil2 peptidylprolyl isomerase (cyclophilin)-like 2 protein_coding Danio_rerio
ENSMUSG00000022771 Ppil2 peptidylprolyl isomerase (cyclophilin)-like 2 protein_coding Mus_musculus

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