C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adrenergic, beta, receptor kinase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100077 ADRBK2 9606 + 22:25564849-25729294 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000324198 ADRBK2-001 25564849-25729294 protein_coding
  ENST00000455558 ADRBK2-002 25565107-25684568 nonsense_mediated_decay
  ENST00000619906 ADRBK2-201 25564912-25723018 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000324198ENST00000455558ENST00000619906
Transcript ID Adipose Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000324198 N/A 2.008±0.83 2.055±1.46 1.207±0.01 0.434±0.00 0.148±0.00 0.441±0.15 0.354±0.09 0.050±0.02 1.142±0.00 N/A 1.530±0.39
ENST00000455558 N/A N/A N/A N/A N/A N/A N/A N/A 0.221±0.00 N/A N/A N/A
ENST00000619906 1.594±0.00 3.271±0.00 3.228±0.98 1.287±0.00 0.715±0.00 N/A 2.124±1.72 1.608±0.61 0.111±0.00 2.716±1.81 1.770±0.87 4.709±0.20

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004UJ CIL_0004UJ_0002 CGP 22:25564849-26031041

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 TAS:IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004703 IEA G-protein coupled receptor kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0006468 IEA protein phosphorylation
GO:0007165 IEA signal transduction
GO:0008277 IEA regulation of G-protein coupled receptor protein signaling pathway
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0031623 IDA receptor internalization
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway
GO:0047696 IEA beta-adrenergic receptor kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013007 adrbk2 adrenergic, beta, receptor kinase 2 protein_coding Danio_rerio
ENSMUSG00000042249 Adrbk2 adrenergic receptor kinase, beta 2 protein_coding Mus_musculus

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