C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: TRIO and F-actin binding protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100106 TRIOBP 9606 + 22:37697004-37776556 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000331103 TRIOBP-013 37754882-37755510 retained_intron
  ENST00000344404 TRIOBP-002 37697621-37774048 nonsense_mediated_decay
  ENST00000403663 TRIOBP-006 37746233-37774140 protein_coding
  ENST00000406386 TRIOBP-001 37697004-37776556 protein_coding
  ENST00000407319 TRIOBP-005 37746228-37760346 protein_coding
  ENST00000413051 TRIOBP-009 37746322-37757963 nonsense_mediated_decay
  ENST00000417857 TRIOBP-010 37751398-37758047 protein_coding
  ENST00000418339 TRIOBP-008 37750997-37757982 protein_coding
  ENST00000428075 TRIOBP-012 37746270-37758135 protein_coding
  ENST00000452519 TRIOBP-011 37751385-37755574 protein_coding
  ENST00000492485 TRIOBP-003 37697621-37726570 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000403663ENST00000406386ENST00000407319
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000403663 33.963±0.00 29.861±0.00 2.142±0.00 2.358±1.18 16.980±9.79 12.433±5.04 13.144±10.08 11.630±10.08 6.648±3.61 13.889±11.17 3.255±0.00 38.908±24.66 52.038±11.49 29.543±4.38
ENST00000406386 N/A N/A N/A 0.250±0.14 N/A N/A N/A N/A N/A N/A N/A 3.442±2.65 N/A N/A
ENST00000407319 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.990±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00099H CIL_00099H_0001 VISTA 22:37683926-38284300
CIL_0008KJ CIL_0008KJ_0001 VISTA 22:37685616-38286450
CIL_00040B CIL_00040B_0001 CGP 22:37686414-37776556
CIL_0008BX CIL_0008BX_0001 VISTA 22:37696030-38296592
CIL_0001D1 CIL_0001D1_0001 CGP 22:37697004-37807436

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005925 IDA focal adhesion
GO:0007067 IEA mitotic nuclear division
GO:0015629 IDA actin cytoskeleton
GO:0017049 NAS GTP-Rho binding
GO:0030047 NAS actin modification
GO:0031625 IPI ubiquitin protein ligase binding
GO:0045159 NAS myosin II binding
GO:0051015 IDA actin filament binding
GO:0051016 NAS barbed-end actin filament capping
GO:1900026 IDA positive regulation of substrate adhesion-dependent cell spreading

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006385 triobp TRIO and F-actin binding protein protein_coding Danio_rerio
ENSDARG00000075870 TRIOBP (2 of 2) TRIO and F-actin binding protein protein_coding Danio_rerio
ENSMUSG00000033088 Triobp TRIO and F-actin binding protein protein_coding Mus_musculus

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