C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: F-box protein 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100225 FBXO7 9606 + 22:32474676-32498829 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000266087 FBXO7-001 32474676-32498829 protein_coding
  ENST00000397426 FBXO7-002 32475257-32498829 protein_coding
  ENST00000420700 FBXO7-003 32474676-32498829 nonsense_mediated_decay
  ENST00000425028 FBXO7-004 32474798-32498829 nonsense_mediated_decay
  ENST00000444207 FBXO7-007 32475593-32483983 protein_coding
  ENST00000452138 FBXO7-006 32475237-32484105 protein_coding
  ENST00000465418 FBXO7-008 32478035-32479231 processed_transcript
  ENST00000484607 FBXO7-010 32487288-32491113 retained_intron
  ENST00000492535 FBXO7-005 32475015-32498829 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000266087ENST00000397426ENST00000420700ENST00000425028ENST00000492535
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000266087 4.814±0.00 N/A 3.002±0.00 9.532±0.00 4.962±0.00 7.295±0.21 2.969±0.91 5.307±1.28 10.611±0.00 6.580±0.00 3.424±1.36 10.157±3.43 14.941±2.82 11.101±0.07
ENST00000397426 7.125±0.00 8.764±0.00 3.547±0.00 14.696±10.04 12.652±0.00 15.590±0.00 3.116±1.98 8.848±4.78 8.813±0.00 23.913±0.00 1.610±0.00 16.112±6.20 20.041±5.37 32.242±5.67
ENST00000420700 7.197±0.00 21.627±0.00 N/A N/A 9.776±0.00 N/A 3.671±0.00 21.528±0.00 N/A 13.670±0.00 N/A 16.426±6.32 15.352±5.12 26.087±1.67
ENST00000425028 9.955±0.00 N/A 2.507±0.00 N/A 13.520±0.00 N/A 3.835±0.00 8.242±0.00 7.631±0.00 12.171±7.39 7.329±0.00 12.435±3.57 18.640±0.46 19.255±4.71
ENST00000492535 0.873±0.00 2.502±0.00 N/A 3.571±0.00 1.068±0.00 N/A 0.624±0.00 N/A N/A 2.169±0.10 0.384±0.00 1.457±0.41 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002NL CIL_0002NL_0001 CGP 22:32413847-32498829
CIL_0002NM CIL_0002NM_0001 CGP 22:32474676-33058372

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000151 IDA ubiquitin ligase complex
GO:0000422 IMP mitochondrion degradation
GO:0004842 TAS ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005739 IDA mitochondrion
GO:0005829 IDA cytosol
GO:0006511 TAS ubiquitin-dependent protein catabolic process
GO:0006626 IMP protein targeting to mitochondrion
GO:0008219 IEA cell death
GO:0016567 IEA protein ubiquitination
GO:0019901 IEA protein kinase binding
GO:0031647 IDA regulation of protein stability
GO:0043234 IDA protein complex
GO:0045620 IEA negative regulation of lymphocyte differentiation
GO:0045736 IEA negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:2000134 IEA negative regulation of G1/S transition of mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059115 fbxo7 F-box protein 7 protein_coding Danio_rerio
ENSMUSG00000001786 Fbxo7 F-box protein 7 protein_coding Mus_musculus

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