C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: neurofilament, heavy polypeptide
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100285 NEFH 9606 + 22:29480230-29491390 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000310624 NEFH-001 29480230-29491390 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000310624
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000310624 0.163±0.00 0.466±0.00 0.130±0.00 29.082±26.01 0.228±0.18 1.015±0.00 0.042±0.03 0.312±0.00 0.068±0.02 0.093±0.08 0.093±0.08 5.049±5.69 0.572±0.17 6.321±2.24

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000226 IEA microtubule cytoskeleton organization
GO:0005198 IMP:IEA structural molecule activity
GO:0005200 ISS structural constituent of cytoskeleton
GO:0005737 ISS cytoplasm
GO:0005739 IEA mitochondrion
GO:0005882 IEA intermediate filament
GO:0005883 NAS neurofilament
GO:0007409 TAS axonogenesis
GO:0008017 TAS microtubule binding
GO:0008219 IEA cell death
GO:0019894 TAS kinesin binding
GO:0019901 IPI protein kinase binding
GO:0030031 TAS cell projection assembly
GO:0030424 TAS axon
GO:0030674 ISS protein binding, bridging
GO:0033693 IMP neurofilament bundle assembly
GO:0045104 IEA intermediate filament cytoskeleton organization
GO:0045110 IEA intermediate filament bundle assembly
GO:0045502 TAS dynein binding
GO:0048936 IEA peripheral nervous system neuron axonogenesis
GO:0060052 IEA neurofilament cytoskeleton organization
GO:0061564 IMP axon development
GO:0097418 IDA neurofibrillary tangle
GO:1902513 IMP regulation of organelle transport along microtubule

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000020396 Nefh neurofilament, heavy polypeptide protein_coding Mus_musculus

Loading