C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: trinucleotide repeat containing 6B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100354 TNRC6B 9606 + 22:40044817-40335808 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000301923 TNRC6B-201 40044817-40335807 protein_coding
  ENST00000335727 TNRC6B-002 40177942-40335808 protein_coding
  ENST00000402203 TNRC6B-001 40045474-40323360 protein_coding
  ENST00000441751 TNRC6B-004 40044817-40156182 protein_coding
  ENST00000446273 TNRC6B-003 40265003-40321799 protein_coding
  ENST00000454349 TNRC6B-202 40177925-40335807 protein_coding
  ENST00000467658 TNRC6B-007 40300856-40301495 retained_intron
  ENST00000489500 TNRC6B-005 40177925-40246362 retained_intron
  ENST00000497559 TNRC6B-006 40276840-40300498 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000301923ENST00000335727ENST00000402203ENST00000446273ENST00000454349
Transcript ID Adipose Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000301923 0.623±0.00 0.936±0.00 N/A N/A N/A N/A N/A N/A 0.352±0.00 0.376±0.00 N/A N/A
ENST00000335727 0.647±0.00 0.803±0.18 N/A 1.258±0.47 1.487±0.60 1.979±0.00 2.599±0.00 0.613±0.00 0.887±0.27 1.090±0.59 0.772±0.78 2.871±0.96
ENST00000402203 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.408±0.03 8.381±0.00
ENST00000446273 N/A N/A 2.315±0.00 N/A N/A N/A 3.083±0.00 N/A N/A N/A N/A 3.179±0.00
ENST00000454349 N/A 1.018±0.06 N/A N/A 0.703±0.20 N/A N/A N/A N/A 0.634±0.20 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005W3 CIL_0005W3_0001 CGP 22:39994949-40335808
CIL_0006F2 CIL_0006F2_0001 CGP 22:40044817-40369367

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0005515 IPI:IEA protein binding
GO:0005829 TAS cytosol
GO:0006417 IEA regulation of translation
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007219 TAS Notch signaling pathway
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0010467 TAS gene expression
GO:0031047 IMP gene silencing by RNA
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0044822 IDA poly(A) RNA binding
GO:0045087 TAS innate immune response
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling
GO:0060213 IMP positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO:1900153 IMP positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074161 tnrc6b trinucleotide repeat containing 6b protein_coding Danio_rerio
ENSDARG00000076389 TNRC6B (2 of 3) trinucleotide repeat containing 6B protein_coding Danio_rerio
ENSDARG00000079723 TNRC6B (3 of 3) trinucleotide repeat containing 6B protein_coding Danio_rerio
ENSMUSG00000047888 Tnrc6b trinucleotide repeat containing 6b protein_coding Mus_musculus

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